Iyini i-vitrification futhi isetshenziswa kuphi?
Le ndlela entsha ifana kakhulu ne-cryopreservation, lapho kukhishwa khona amaqanda omzimba wesifazane wesifazane. Okubalulekile kulokhu kuvela, ikakhulukazi, phakathi ne-IVF, lapho ukufika kokuqala kungaphumeleli. Ukuze ungaphinda ukhethe i-oocyte, sebenzisa i-vitrified. Qaphela ukuthi i-oocyte i-ovules encane ibekwe ngqo kuma-ovari.
Inzuzo enkulu yale nqubo yiqiniso lokuthi, uma kuqhathaniswa ne- cryopreservation, i- vitrification ivumela isikhathi eside ukugcina amangqamuzana obulili ngaphandle kokunciphisa ukusebenza kwabo. Ngaphezu kwalokho, le ndlela iyanciphisa cishe amathuba okulimala kwe-oocyte phakathi nenqubo yokuqandisa, futhi ngesikhathi esifanayo, ukusebenza kwezinhlelo zokusabalalisa okufakelwayo akunciphisi.
Njengoba sekushiwo ngenhla, le nqubo isetshenziselwa ngokuyinhloko ngezinqubo zokukhulelwa kwe-in vitro. Njengomthetho, bawusebenzisa lapho:
- ukungenakuthola ukuthola i-spermatozoa ngokuqondile ngosuku lokuqothula ngesikhathi se-IVF;
- akunakwenzeka ukuhlela ukukhulelwa esikhathini esizayo esiseduze (uma kukhona ukuphikisana okuvela ohlelweni lokuzala noma ukungabi nesifiso kumfazi ngokwayo, isibonelo);
- ngaphambi kwekhemotherapy kwabesifazane abanomdlavuza (ukukhipha ithonya lama-chemotherapy ngamaseli ocansi);
- Isidingo sokugcina ama-oocyte abo ngemuva kokugcoba.
Yiziphi izinzuzo zalendlela?
Lapho kutholakala ama-oocyte asanda kuzalwa, ama-oocyte, inqubo yokuqhwaza yenziwa ngesikhathi esifushane. Ngenxa yale nsigu, ama-crystals ezincane ezincane, ezingalimaza igobolondo le-oocyte, asinaso isikhathi sokwenza. Ngakho-ke, emva kokuqhaqhazela, odokotela bangakwazi ukuvuka ku-98% wamaseli asegciwane asempilweni asebenzayo. Kumele uqaphele ukuthi nge-cryopreservation, akukho ngaphezu kuka-60% okusinda.
Eqhutshwa ngokuphumelela kwalendlela, ucwaningo luye lwabonisa ukuthi ama-oocyte angagesi ahlonyiswa cishe nemvamisa efanayo nalawo maseli asemzimbeni wesifazane. Lapho kwenziwa ukuguqulwa kwe-cryopreservation, kunesimo esinjalo njengokuqina kwamagqabha e-oocyte. Leli qiniso liyanzima kakhulu ukungena kwesidoda emaqanda.
Yiziphi izici ze-vitrification?
Ngokushesha ngaphambi kokuqala kokuvuthwa emzimbeni wesifazane, ukwelashwa okwenziwe nge-hormone kwenziwa ukugqugquzela ama-ovari. Ngokushesha ngaphambi kokuba kukhululwe i-ovum evela ebukhosini, i-ultrasound inikezwa. Lokhu kwenza kube lula ukucacisa ukuthi amaqanda avuthiwe afanele yini ukuvivinya umzimba. Uma zingatholakali - inqubo yokuvuselela iphindaphinda futhi.
Inqubo yenziwa ngaphansi kwe-anesthesia jikelele. Ngesikhathi esifanayo, ukufinyelelwa kwenziwa nge-transvaginally, usebenzisa inaliti ekhethekile. Le nqubo ilawulwa yimishini ye-ultrasound. Ama-oocyte aqoqiwe anqamule futhi angagcinwa isikhathi eside.
Ngakho-ke, kungashiwo ukuthi i-cryopreservation ne-vitrification yizindlela ezimbili ezifanayo, ezenziwa ngendlela efanayo, kodwa zinezici zazo ezikhethekile zokufeza. Muva nje, i-IVF ene-vitrification isetshenziswe ngokuqhubekayo, kuhlanganise nomgomo wokwakha ibhange lama-oocyte emitholampilo yokwelapha yokubeletha.