I-hormone ye-prolactin yenziwa emgodini we-pituitary wangaphakathi. Ukusebenza okuvamile kwe-hormone ye-lactation kwenzeka ngesikhathi sokulala, ukusondela okusondelene. Igama lenye igama elithi "i-hormone yokucindezeleka" i-prolactin yenziwa ngenxa yokwanda kwezimfanelo emazingeni ngesikhathi sokuqubuka komzwelo nokwenyama okuhlukahlukene. Okokuthi, i-hyperprolactinemia engapheli ivame ukubonwa kunoma iziphi izimo ezicindezelayo zomzimba.
Kubesifazane abavamile, i-hormone prolactin ihluka ngezinsuku ezahlukene zokujikeleza kokuya esikhathini futhi isukela ku-4.5 ng / ml ukuya ku-49 ng / ml. Futhi ukubaluleka okukhulu kwezinga kuphawulwa ngesikhathi sesigaba se-ovulatory somjikelezo. Ngesikhathi sokukhulelwa, isimiso sizoba yisilinganiso esiphakeme, futhi ku-trimester yesithathu singakwazi ukufinyelela ku-300 Ng / ml. Kubantu, amazinga e-prolactin avela ku-2.5 kuya ku-17 ng / ml. Njengoba ubona, isibonakaliso asikwazi ukushintshashintsha kakhulu kunomzimba wesifazane.
Imisebenzi yeprolactin
Cabanga ukuthi i-prolactin ye-hormone iyabangela nokuthi yimiphi imisebenzi eyithatha kubameleli bezocansi ezahlukene. Ngaphezu kokusebenza ohlelweni lokuzala, i-prolactin inomthelela ekukhutheni umzimba. Ngokuyinhloko, phakathi nokuthuthukiswa kwe-intrauterine ye-fetus, i-prolactin yanda ukuyivikela emiphumeleni yamasosha omzimba omama. Imiphumela eyinhloko ye-hormone yabesifazane ifakwe ngezansi:
- Ukuthinta izilonda ezincelisayo. Ngaphansi kwethonya le-hormone, ukukhula kwezigulane zamathambo kuvuselelwe, futhi ukulungiselela kwabo ukukhipha i- lactation . Futhi kuyingxenye ekugqugquzelweni nasekulawuleni ukwakhiwa kobisi ngesikhathi sokuncelisa ingane.
- Omunye wemisebenzi ebaluleke kakhulu ukugcina ubuhle bomzimba ophuzi ovary. Ngakho-ke, izinga eliphezulu le-progesterone elidingekayo ekubelethweni okujwayelekile ligcinwa.
- Umphumela we-prolactin ekubunjweni "kobuthakathaka bokubeletha" kanye nokuphendula okuhambisana nokuziphatha kwaphawula.
- Ilawula umsebenzi wezinhlayiya ze-adrenal (prolactin igqugquzela ukukhiqizwa kwe-androgens).
Emadodeni, i-pituitary hormone prolactin inomphumela olandelayo emzimbeni:
- Ngenxa yobuhlobo obuseduze no-LH no-FSH, i-prolactin ye-hormone ingenza izenzo zezinye amahomoni ezilawula umsebenzi wezocansi. Kubandakanya ukulawula ukwakheka kwe-testosterone.
- Ihlanganyela ekulawulweni kwe-spermatogenesis.
- Ikhuthaza ukucinwa kwe-prostate gland.
Ngakho-ke, kuyacaca ukuthi i-hormone prolactin ibonisa isimo sesimiso sokuzala sowesifazane nowendoda.
Izimpawu nge prolactin eyanda
I-hormone prolactin eyedlulele idala ukuphazamiseka okukhulu kokusebenza, kokubili kwabesifazane namadoda.
- Esikhathini sokuqala saleso sifo sibonakala ukwehla kwesifiso sobulili, okuyinto ngokuqhubeka kwe-hyperprolactinemia kuholela ekusebenziseni ukuzala okungavamile.
- Abesifazane bane-anorgasmia kanye nezinkinga zokujikeleza esikhathini. Ukuya esikhathini esiqhamukayo kuya phambili. Uma ukuhlolwa kwembula ukungabi khona kwe-ovulation. Lokhu kungenxa yobuhlobo obuseduze phakathi kwama-hormone ocansi kanye ne-prolactin, ngoba izinga eliphakeme le-prolactin linciphisa ukukhiqizwa kwe- LH ne-FSH . Futhi lokhu kuyimbangela yokungasebenzi.
- Kungase kube nokukhishwa kwamagundane amancane.
- Emadodeni, ukuphulwa komsebenzi wezocansi nezinga eliphakeme leprolactin kubonakala ngokungasebenzi kahle kwe-erectile.
- Futhi, ukulala ngokobulili kungase kungabi ne-ejaculation ne-orgasm. Uma kuhlaziywa i-spermogram, kutholakala inani elincane le-spermatozoa, elibhekiswe ekunciphiseni ukuhamba kwabo kanye nokuba khona kwezimo ezihlukahlukene esakhiweni.
- Ukwanda kwe-prolactin kukhuthaza ukwanda kwezigulane zamathambo emadodeni. Lesi simo sabizwa ngokuthi i-gynecomastia.