I-grenal adrenal ikhiqiza i- 17-OH-progesterone , ebesimame abesifazane abanomthwalo wemithethonqubo ye-hormone yomjikelezo wokuya esikhathini. Izinga lalo alihlali njalo futhi lihlukahluka kulo lonke umjikelezo: lihlala liphansi ngaphambi kokuvuthwa, likhuphuka futhi lihlala phezulu emkhathini wesibili womjikelezo. Uma kungabikho ukukhulelwa, lapho kuqala umjikelezo olandelayo, izinga le-17-OH-progesterone liwa.
Izimbangela zokwanda kwe-17-OH-progesterone
Ukukhulelwa kungenye yezizathu zokuthi kungani i- 17-OH-progesterone iphakanyisiwe . Kakade emva kokukhulelwa nokufakelwa, izinga le-hormone liqala ukuphakama.
Uma kungekho ukukhulelwa, kunezinye izizathu, ngenxa yokuthi i-17-oh-progesterone yanda kangakanani, izifo ezinjengama-tumor adrenal noma ama-ovarian, ama-adrenal hyperplasia angama-congenital afakiwe.
Izimpawu zokwanda kwe-17-OH-progesterone
Ngokuvamile, izinga le-17-OH-progesterone:
- emadodeni avela ku-0.2 kuya ku-2.3 ng / ml;
- kwabesifazane besigaba sokuqala somjikelezo kusuka ku-0.2 kuya ku-1.2 ng / ml;
- okwesibili - kusuka ku-1.0 ukuya ku-4.5 ng / ml;
- ekukhulelwe kusuka ku-2,0 kuya ku-12.0 ng / ml.
Kungenzeka ukusola ukwanda kwezinga le-17-OH-progesterone kubesifazane abanokubonakala kokukhula kwezinwele emzimbeni nokunciphisa kwabo. Ukwandisa izinga le-hormone kuholela ezikhathini ezingavamile kumfazi noma i-amenorrhea ephelele. Futhi, ukwanda kwe-17-OH-progesterone kuholela ezinkingeni zezinye izitho nezinhlelo:
- Izinga likashukela egazini landa;
- zikhona izinkinga esikhumbeni nasendlini;
- ukwanda kwengcindezi yegazi kanye ne-cholesterol;
- kukhona ukuphazamiseka emsebenzini wenhliziyo yowesifazane kunoma yikuphi ubudala.
Ukwelashwa kokwanda kwe-17-OH-progesterone
Ukulungisa i-hormone ephakeme ngemva kokunquma izinga layo egazini linikeza izidakamizwa ze-hormone (i-Prednisolone, i-Dexamethasone). Inkambo yokwelashwa ithatha izinyanga eziyisithupha, ukwesulwa kokwelashwa akunakwenziwa ngokungazelelwe: umthamo wamahomoni uhlale ulungiswa udokotela.