I-pro-prote-17-OH iyingxenye ephakathi kokuhlanganiswa kwamahomoni adrenal: glucocorticoids, estrogens kanye androgens. 17-ON progesterone ibhekisela kuma-hormone wesilisa. Emzimbeni wesifazane, i-17-OH progesterone ikhiqizwa yi-adrenals nama-ovaries.
Imiphumela ye-17-OH progesterone emzimbeni wesifazane
Kuwesifazane omzimba, i-17-OH progesterone ithinta amathuba okukhulelwe kanye nesikhathi sokubeletha, njengoba le hormone iqhaza emsebenzini wokuzala. Ngaphezu kwalokho, ama-hormone wesilisa emzimbeni wesifazane ayingxenye ekuqaleni kokukhulelwa, abangela ukuguqulwa kwamahomoni abe yi-estrogens. Emzimbeni wesifazane, ama-hormone wesilisa akhiqizwa kancane kunabesilisa. Kodwa uma banda ngaphezu kwezinga lokuphila, i-hyperandrogenia iyaqala. Ezimweni eziningi, lesi sifo sitholakala ngaphambi noma ngesikhathi sokuthomba.
Amanani ka-17-OH progesterone
Izinga le-17-OH progesterone liphakanyisiwe ekuqaleni kokuzalwa kwengane, ikakhulu uma izalwa ngaphambi kwesikhathi. Ngemuva kweviki lokuqala lokuphila kwengane, izinga le-hormone liyancipha futhi lihlala kuze kube yilapho sekukhulelwa. Ngemuva kokuqala kokukhulelwa, izinga le-17-OH progesterone likhuphukela ezingeni le-hormone kubantu abadala:
- 0.2 - 2.3 Ng / ml kumadoda;
- 0.2 - 1.2 ng / ml kwabesifazane besigaba sesilandelayo;
- 1.0 - 4.5 Ng / ml kwabesifazane besigaba sokuqamba;
- 2.0 - 12.0 ng / ml kwabesifazane abakhulelwe.
17-OH progesterone ephakanyisiwe - izimbangela
Isizathu sokwanda kwe-17-OH progesterone kungenzeka kube khona ukugula okufana nalokhu:
- i-hyperplasia engama-congenital;
- ukuntuleka kwe-21-hydroxylase ne-11-b hydroxylase;
- izicubu zama-ovari nama-gland adrenal.
Amazinga aphakanyisiwe we-17-OH progesterone abonakala ngesikhathi sokukhulelwa, okuyinto evamile yokuphila. Uma i-pro-proton-17-OH iphakanyiswa ngaphezu kwesikhathi sokukhulelwa, kufanele uxhumane nodokotela ukuze uthole iseluleko futhi uhlolwe ama-hormone.
17-OH progesterone ephakeme - izimpawu
Izinga eliphakeme le-17-OH progesterone lingabangela izimpawu ezinjalo kubesifazane:
- ukukhula kwezinwele ngokweqile nokunciphisa;
- ukungabikho noma ukuya esikhathini okungavamile;
- ukwephula izinga leshukela legazi;
- i-acne .
Uma kungekho ukwelashwa okwanele, izimpawu ezinjalo zingathuthuka emzimbeni omkhulu, njengokuthi:
- ukwephulwa kwe-insulin ukumelana;
- isifo sikashukela mellitus;
- umfutho wegazi ophezulu;
- i-cholesterol eyanda;
- izinkinga ngenhliziyo.
Lapho kukhona i-syndrome ye-polycystic ovaries, i-hormone 17-OH progesterone inganda, ngakho-ke, ekutholeni lesi sifo kuyadingeka ukudlulisa ukuhlolwa kwamahomoni.
Ukuphakama kwe-17-OH progesterone ne-acne
Esinye sezibonakaliso zokwanda kwe-17-OH progesterone yizikhukhula zesikhumba noma ama-pimples. Lapho izinga le-hormone liyehla, uphawu lwe-symptomatology luyahamba. Ngakho-ke, uma uphatha le nkinga ye-dermatological, kuyadingeka ukuthi ungasebenzisi nje kuphela izindlela zokuzithokozisa zendawo, kodwa futhi uvuselele imvelaphi ye-hormonal.
Indlela yokunciphisa progesterone ka-17-OH?
Ukwelapha ngezinga eliphakeme lika-17-OH progesterone lenziwa yimithi ye-hormonal. Isibonelo, dexamethasone noma i-methylprednisolone. Uma uthatha le mithi, kungase kube nokwanda kwesisindo, ngoba banamanzi. Ayikho eminye imiphumela emibi, ngoba ekwelapheni ukungasebenzi
Uhlelo lwezokwelapha nokwamukelwa kwezidakamizwa lubekwa udokotela kuye ngokuthi kubonakala kanjani emitholampilo yesifo, izigaba zomjikelezo wesimiso. Umthamo wansuku zonke kufanele uhlukaniswe ngamanani amaningi. Isikhathi esiphakathi kokuthatha isidakamizwa kufanele sibe okufanayo. Ungathatha imithi emva kokudla, uma kunezinkinga ngepheshana lesisu. Ngezikhathi ezithile, udinga ukuhlolwa kwegazi, hlola izinga le-hormone nokusebenza kokwelashwa.
Ngesifo sokubeletha ngaphambi kokuqala kokukhulelwa, inkambo yokwelashwa ingadlulela ezinyangeni ezintathu kuya kweziyisithupha.