Okokuqala, sizoqonda lesi sigama: i-metaplasia iyishintsho ezindaweni eziphathekayo, ukutholakala kwayo ngezibonakaliso zenye izicubu ngaphakathi kokuhlukahluka kweqabunga elilodwa lama-embryonic, okungukuthi, izicubu ze-onetiotype eyodwa. Ngokuvamile lokhu kwenzeka ku-epithelial or tiscutic tissues. Ngokwezigaba zemitholampilo, i-squamous cell metaplasia yomlomo wesibeletho ibhekisela ezinkingeni ezinobunzima.
Inqubo yenqubo ye-metaplasia
I-metaplasia ye-epithelium yomlomo wesibeletho iyenzeka isikhathi eside ngokwanele ngesikhathi sokwanda nokuhlukaniswa kwamaseli amasha, okuthiwa, agcina noma ama- stem . Emgodini wesibeletho, inqubo echazwe kwenzeka ngokuqondile ngenkathi ukwanda kwamaseli. Ngokuvamile, amaseli we-single-layer-epithelium ye-prismatic (isici somsele womlomo wesibeletho) athathe amangqamuzana amangqamuzana angama-multilayered flat (asezindaweni zangasese). Noma ukuhamba ngezinambuzane zamangqamuzana e-epithelium ezinamaqabunga zibe amangqamuzana angama-cylindrical. Ngokuvamile, kukhona umugqa obonakalayo, ocacile phakathi kwale epithelium.
Izimbangela ze-metaplasia yomlomo wesibeletho
Ngokuvamile imetaplasia iyindlela yokubhekana nesifo esingapheli, isibonelo, ukuvuvukala, ukutheleleka, ukuguquka kwesimo sangemuva emzimbeni wesifazane, ukuphulwa kwe-pH yesifazane, noma ukubonakaliswa kokuphulukiswa komkhuhlane wesibeletho . Lapho ithonya elinonya lezinto ezicasulayo liphela, izicubu zibuyela esimweni sayo esijwayelekile sokuziphatha.
Yini okufanele uyenze nge-metaplasia?
Akudingekile ukuba u-epithelium we-metaplastic ngokwayo ungakabi khona isikhathi esithile, akuyona into eyakhekayo futhi ayibheki ngisho nezimo ezingenakuqhathaniswa. Nakuba akuyona inqubo enhle futhi kudinga ukuhlolwa okungeziwe nokucaciswa kwe-factor causal. Kufana nokuphendula okuguquguqukayo komzimba ukuguqula izimo, ukunikeza isignali mayelana nenqubo ekhona ye-pathological. Emva kwalokhu, ukwelashwa komuntu ngamunye we-metaplasia yomlomo wesibeletho kufanele kwenziwe. Kunoma yikuphi, lesi sifo sidinga ukunakekelwa okujwayelekile ngudokotela oya khona.