Ama-Platelets amancane amangqamuzana egazi abhekene necala lokuvala i-fluid biological. Bahlanganyela:
- ekuvimbeleni ukuphuma (hemostasis);
- ekondleni izindonga zegazi.
Inqubo ye-aggregation aggregation ivela kanjani?
Uma nje sithola ukusika kancane, umzimba uveza inkinga. I-thrombocytes igijimela ezitheni ezimele, eziqala ukuhlangana ndawonye. Lesi senzo sibizwa ngokuthi i-aggregation. Kwenzeka ngezigaba ezimbili:
- Okokuqala, amaplatelet ahlangene ndawonye - lokhu kuyisigaba sokuqala sokwakhiwa kwe-thrombus.
- Bese banamathele ezindongeni zezimpahla.
Ngemuva kwalokhu kwendwangu yamaplatelet ezinye izakhi, namanje amaplatelet alandela, futhi ngenxa yalokho i-thrombus ikhula kuze ivimbele izindonga eziphukile zemithambo yegazi ukuze igazi lingaphumi. Kodwa-ke, kukhona ingozi esongela ukwakheka okwedlulele kwezindwangu zegazi - lokhu kuhlaselwa yinhliziyo, ukushaya.
Kungakhathaliseki ukuthi yikuphi okungavamile, sicela uxhumane nochwepheshe.
Isivivinyo segazi sokuvala
Ukuze kuhlolwe i-platelet aggregation kuyadingeka ukuthatha ukuhlolwa kwegazi:
- Uma kukhona izivunguvungu kusuka ekushayweni okuncane, amanxeba awaphuluki kahle, kaningi kukhona igazi elivela ekhaleni - lokhu kuyisignali ukuthi i-coagulability yegazi iyancishiswa.
- Uma kukhona ukuvuvukala - ngokuphambene nalokho, i-coagulability yanda.
Ukuhlaziywa kwenziwa ngokusungula i-aggregation inducer nokubona ukusabela. Njenge-inducer, izinto ezenziwe ngama-chemical clot-forming, ezisondelene kakhulu nemvelo, ziyasetshenziswa.
Ukuhlelwa kwamaplatelets kuhlolwe ngosizo lwababantu abanjalo:
- i-adrenaline;
- izingxenye zodonga lwamasongo: i-adenosine diphosphate (ADP);
- i-ristocetin (i-ristomycin);
- i-collagen;
- i-serotonin.
Ukwahlukana okungajwayelekile kwamaplatelet kunqunywa ngaphandle kwama-inducers.
Ngaphambi kokuba uhlole, kudingeka ulungiselele ngokucophelela ukuhlolwa kwegazi ukuze kube okulungile. Ukuze wenze lokhu, kufanele ulandele le mithetho:
- Ngaphambi kokuthatha uhlolo, yeka ukuthatha zonke izidakamizwa ze-aspirin (i-dipyridamole, i-indomethacin nabanye) kanye nama-antidepressants.
- Ukuhlaziywa kuthathwa esiswini esingenalutho, amahora angu-12 emva kwesidlo sokugcina, ikakhulukazi akusifisi ukudla ukudla okunamafutha.
- Ungazitholi ngokweqile ngokomzimba, thola.
- Ukuze usuku lungaphuzi ikhofi, iziphuzo ezidakayo, ukuba ungadli igalikhi futhi ungabhemi.
- Uma umzimba unesimiso sokuvuvukala, ukuhlaziywa kufanele kuhlehliswe.
- Kubalulekile ukwazi ukuthi ngesikhathi sokuya esikhathini, ukwehla kwegazi kukhishwa kubesifazane, futhi lokhu kungathinta umphumela wokuhlaziywa.
Umkhuba we-platelet aggregation
Inani elivamile lamaplatele egazini lisho ukuthi umuntu unegazi elihle, ama-tissue kanye nezitho zinikezwa umoya-mpilo nensimbi ngobuningi obanele.
Umkhuba wokuqukethwe kwamaplatelet usuka ku 200 kuya ku-400 x 109 / l. Futhi, ekucwaningweni kwe-laboratory ye-stopwatch kulinganisa isikhathi lapho ama-aggregate amakhulu ama-platelet akha khona. Isikhathi esivamile sokwakheka imizuzwana engu-10 kuya kwengu-60.
Ukwandiswa kweplatelet aggregation
Ukuze uqonde uhlobo luni lwesimo, lapho ukukhula kweplatelet kukwandiswa, udinga ukunaka lokhu: igazi likhulu, lihamba kancane kancane emithanjeni yegazi, liqhuma. Lokhu kubonakala njengomuzwa wokuzibulala, ukuvuvukala. Thrombocytosis enjalo kwenzeka lapho:
- ukusatshalaliswa kwe-atherosclerosis yemithwalo yegazi;
- isifo sofuba;
- isifo sikashukela mellitus;
- i-leukemia;
- umdlavuza wesisu noma izinso;
- lymphogranulomatosis ;
- emva kokususwa kwephutha;
- i-sepsis.
Igazi elimnyama lisongela izimo ezinjengalezi:
- i-infarction ye-myocardial;
- i-thrombosis yemilenze yemilenze;
- ukushaywa ;
- ukufa okuphazima kweso kusuka ekujuleni kwe-aorta nge-thrombus ehlanganisiwe, njll.
Ukwehlisa ukuhlukunyezwa kwamaplatelets
Njengoba inamba encane yamaplatelet emithanjeni yegazi iba yi-brittle, ukuphuma kwegazi kuyama ngezinkinga.
Uma i-platelet aggregation inciphise, udinga:
- Gwema ukulimala.
- Qaphela izidakamizwa nokuphuza utshwala.
- Yidla kahle, uqede ukudla okuneziphuzo kanye nosawoti.
- Kukhona ukudla okunezinsimbi (ubhontshisi, ama-apula, u-buckwheat, inyama, inhlanzi, iparsley, pepper, amantongomane, isipinashi).