Inqubo yegazi coagulation iqhubeka ngezigaba eziningana. Okwokuqala ukubunjwa kwe-thromboplastin, okwesibili yi-thrombin ukwakheka, kanti okwesithathu yi-fibrinogenesis. Ukugeleza okujwayelekile kwesigaba ngasinye egazini kufanele kube i-anticoagulant. Uma izinto zemvelo zanele, ke zilingiswa - izidakamizwa zijojowe.
Izinkomba zokusebenzisa ama-antiplatelet agents
I-Antiagreganty - izidakamizwa ezinomthelela ocindezelayo ohlelweni lokugaya igazi. Ngokusho kwe-antiticoincidence, bahlukaniswe ngamaqembu amabili:
- isenzo esiqondile (heparinoids, heparin);
- isenzo esingavamile (izakhi ze phenylidandione ne-oxicumarin).
Namuhla, kukhona nama-antiplatelet amanxusa wesizukulwane esisha - ukungafani. Unomthelela wokuvimbela amandla okuhlanganisa ama-platelet.
Ukuqokwa kwazo zonke amaqembu ezidakamizwa kungaba yilowo nalowo noma ndawonye. Izimpawu eziyinhloko zokusetshenziswa kwe-anticoagulants yizibonakaliso zegazi elingenayo i-hypercoagulable (isimo se-prethrombotic) kanye nenqubo ye-thrombotic yezindawo ezihlukile. Isiguli sinconywa ukuba sithathe le mithi ngisho nenqubo ye-thrombotic ohlelweni lwe-coronary artery, njengoba lena ingenye yezindlela eziphumelelayo zokuvimbela i- infarction enkulu ye-myocardial yokugxila emzimbeni.
Ukungahambisani nokusetshenziswa kwamagciwane e-antiplatelet
Ama-antiplatelet wamanje angakwazi ukubekwa uma isiguli sinesifo:
- amadivaysi okugaya (ngisho nasezintweni ezinomkhuba wokuphuma kwegazi);
- izinso ezinezimpawu ze-hematuria;
- isibindi esinokukhubazeka okunzima komsebenzi wayo.
Akunconywa ukuthi uthathe imithi yale nkampani uma kunezinkinga zokuhluleka kwezinso, ukuphulwa kwezinqubo ze-haemostatic, ukuntuleka kwe-C-no-K-vithamini kanye ne-aneurysm yenhliziyo enamandla.
Lezi zidakamizwa zingabangela imiphumela emibi. Ziyabonakala ngokukhethekile lapho zisebenzisa i-anticoagulants yesenzo esiqondile noma esingavamile. Ukungaboni ngaso sonke isikhathi akusho neze umphumela omubi emzimbeni.
Imiphumela emibi kakhulu ye-antiplatelet agents yilezi:
- ukusabela okweqile;
- ikhanda;
- izinkinga ezibuhlungu;
- ukuphuma kwezinye izindawo.
Uhlu lwama-antiplatelet agents
Ama-anticoagulants of effect ngqo aphazamisa ngqo izici zegazi coagulation esiteshini sezinsiza. Umthelela wokwelapha nge-injection emangcwabeni kwenzeka cishe ngokushesha futhi uhlala amahora angu-6. Uhlu lwamaseli we-antiplatelet walesi sigaba luhlanganisa:
- I-Heparinolds;
- I-Heparin;
- U-Arvin;
- I-calcium heparinate;
- I-Chondroitin sulfates A no-C.
I-Heparin evame ukusetshenziswa kakhulu. Ngokushesha kuvimbela ukubunjwa kwe-fibrin futhi kuvimbela ukuhlukumeza kwamaplatelet wegazi.
Uhlu lwamagadagregantshi wezenzo ezingaqondile luhlanganisa:
- Dicoumarin;
- I-Cincumar;
- Nafarini;
- I-Neodikumarin;
- I-Phenylin;
- Omefin.
Zivimbela ukugaya igazi kuphela emzimbeni. Umphumela ngemuva kokusebenza kufaka amahora angu-24-72 futhi ihlala ezinsukwini ezimbalwa. Kungenxa yalesi sakhiwo ukuthi izidakamizwa zaleli qembu zilula kakhulu ukwelashwa kwesikhathi eside.
Izigaba ezihlukaniswa ama-antiplatelet agents zihlala endaweni ekhethekile. Konke ngenxa yokuthi abanethonya elincane emsebenzini we-coagulation wegazi. Kodwa ngesikhathi esifanayo bavimbela noma bavimbe izakhiwo zokunamathisela-aggregation zamacwecwe. Ngakho-ke, ngokuhambisana nezinye izidakamizwa kanye nama-antiplatelet agents, bona
- I-Butadione;
- I-Papaverine ;
- I-Anturan;
- Indomethacin;
- Imizine;
- I-Carbocromene;
- I-Parmedin.
Konke lokhu okungafani nokuqapha kumele kubekwe kubantu abaneminyaka yobudala kanye nobudala.