Esikhathini esifanele sokuthola ukuthi umuntu osolakala ukuthi u- endometriosis uyifinyeleleka kahle futhi ngesikhathi esifanele, indlela yokuqhamuka kwamanye amazwe isetshenziswa kakhulu. Ikakhulukazi, oncomarker elinjalo njengoba CA-125 noma isifo antigen CA-125.
Inkomba ye-CA-125 ye-endometriosis ibaluleke kakhulu, ikakhulukazi esiteji sokuqala sokutholakala kwezifo.
Umkhuba we-CA ngu-125 we-endometriosis
Izinga le-CA-125 ekupheleni kwe-endometriosis linqunywa ku-peritoneal fluid kanye ne-serum. Ngaphezu kwalokho, ngokuvamile lesi simpawu somdlavuza sihlale sikhona emathanjeni we-endometrium, kanye nasemanzini omzimba we-mucinous ne-serous webele. Uma izithiyo zemvelo zingaphuliwe, ngakho-ke azingena emgodleni wegazi, futhi ukwanda kwe-CA-125 akukwenzeka endleleni yokukhanya nephakathi kwe-endometriosis.
Ukukhulisa izinga le-CA-125
Amazinga aphakeme we-CA-125 angabonwa kuphela ekupheleni kwe-endometriosis. Kungabonakaliswa futhi:
- ngesikhathi sokuya esikhathini;
- engxenyeni yokuqala yesithathu yokukhulelwa;
- I-1% yabesifazane abanempilo;
- ezigulini ezine-neoplasms ezingekho ezimbi;
- kwezinye iziguli ezine-neoplasia engavumelani nomzimba.
Ukuphakama kwe-CA-125 ku-endometriosis
Uma i-CA-125 iphakanyisiwe ku-endometriosis, ke-ke, njengoba le glycoprotein isakhiwe yi-derivatives ye-coelomic epithelium, iyimpawu zomdlavuza we-ovarian . Ngakho-ke, ukwanda kwezinga le-CA-125 ekupheleni kwe-endometriosis kungabonisa ukubikezelwa okungathandeki kakhulu kwempilo yowesifazane.
Ngokusekelwe kulokhu okukhulunywe ngakho, kungacaciswa ukuthi ukwaziswa kwalokhu kuhlaziywa kubonakala kuphazamisekile. Odokotela bathi ku-80% amacala adingekayo ukuqhuba uchungechunge lwezocwaningo ngaphambi kokubeka ukuxilongwa okuthembekile - endometriosis. Kodwa uma isifo sitholiwe, izinga le-oncoprotein CA-125 lingaphumelela libe yinkomba yokuphumelela kwemithi enqunyiwe.