Ezifo zesifo se-thyroid noma ngemuva kokwelapha kwabo, iziguli zibekiwe ukuhlaziywa, kepha akubona wonke umuntu owazi ukuthi uhlobo luni lwe-hormone nokuthi yiziphi imisebenzi zalo emzimbeni.
Iyini i-hormone yamahhala e-T4 futhi iyini inesibopho?
I-T4 yamahhala i-hormone eline-iodine ekhiqizwa ngamaseli wegciwane futhi ibizwa ngokuthi i-thyroxine noma i-hormone ye-thyroid. Iningi le-hormone lisefomu eliboshwe ngamaprotheni elibuthelela ezintweni zomzimba zamaseli wegciwane. Uma kunesidingo, kungena egazini njengeH4m hormone. Eminye yayo ihamba emzimbeni ngendlela yamahhala. Lona i-hormone yamahhala e-T4, eyabangela ukusheshisa kwe-catabolism emzimbeni, okungukuthi, inqubo yokuthola amandla avela ku-glycogen namafutha, kanye nokugcwala kwamangqamuzana omzimba nge-oxygen. I-Thyroxine ibhekwa njenge-hormone eyinhloko ye-gland yegciwane futhi ngokusho kwemiphumela yokuhlaziywa ezingeni layo egazini, umuntu angakwazi ukwahlulela umsebenzi we-gland ngokwayo.
Umkhuba we-hormone yamahhala e-T4 egazini
Inani le-thyroxin emadodeni nakwabesifazane lihlukile. Lokhu kungenxa yokuthi ngesikhathi sokukhulelwa izinga le-hormone T4 landa kakhulu. Emva kweminyaka engama-40, izinga le-hormone liqala ukwehla kokubili abesifazane nabesilisa. Isilinganiso sayo esiphezulu sezingqimba ze -roid siqala ekuseni, kusukela ngo-8 kuya ku-12, futhi ebusuku le nqubo iyancipha.
Inani le-hormone T4 lithinteka yizinkathi zonyaka. Ekwindla nasebusika, ukuhlushwa kwayo egazini kuphakeme kunasehlobo nasehlobo. Izinga le-hormone T4 mahhala kuma-laboratories ahlukene lilinganiswa nethimba lazo lezi-reagents, ngakho-ke amanani wezinkomba angase ahluke. Amafomu we-Label ahlale ekhombisa izinga elivumelekile lamazinga we-hormone namayunithi wokulinganisa. Kulaba besifazane ngesikhathi sokukhulelwa, ama-T4 awo amisiwe.
Izimbangela zokunciphisa izinga le-hormone ye-T4 yamahhala
Izinga le-hormone liyancipha:
- uma ukwelashwa kwesikhashana kwe-hyperthyroidism kucatshangwa ngokuthatha imithi ephazamisa ukukhiqizwa kwe-thyroxine;
- lapho ingubo yegciwane noma ingxenye yayo isuswe ngokuhlinzwa;
- kukhona isifo esizimele esisodwa lapho ama-antibodies akhiqizwa emzimbeni ngokumelene ne-follicles ye-gland yegciwane;
- ekwelapheni i-hyperthyroidism nge-iodine yama-radioactive
- ngokuntuleka kwe-iodine emzimbeni;
- uma ukudla okunomthamo wephrotheni kunciphile;
- i-hypothyroidism ;
- ngenkathi ethatha imithi ethile yezenzo ze-antifungal nokulwa nokuvuvukala.
Uma i-hormone ye-T4 yamahhala iyancipha, izimpawu ezilandelayo ziyabonakala:
- inzuzo yesisindo;
- isikhumba esomile;
- ukukhathala ngokuzikhandla okuncane ngokomzimba;
- ukuphazamiseka kokuya esikhathini kwabesifazane.
Kumele kuqashelwe ukuthi ukwehlisa umsebenzi we -roid akukwazi ukuphulukiswa ngokuphelele, kodwa kungenzeka ukwandise inani le-thyroxin ngokuthatha i-analogue yalo yokufakelwa. Ngokuphishekela isibalo esincane, abesifazane abaningi bathatha i-thyroxine ukuze ulahlekelwe isisindo. Lokhu akufanele kwenziwe, ngoba okokuqala kungumuthi, hhayi ukwesezela kokudla.
Izizathu zokwandisa izinga le-hormone yamahhala e-T4
Isizathu esivame kakhulu sezinga le-thyroxine eliphakeme yisifo se-Basedova.
Kanti nezizathu zokwanda kwe-hormone ye-T4 yamahhala yi:
- isikhathi sokuhamba kwesikhathi;
- ukuvuvukala kwegciwane le-thyroid;
- ukwelashwa kwesibindi nezinso;
- ukuthatha amanani amaningi e-aspirin, i-insulini;
- izicubu zegciwane le-thyroid.
Uma i-hormone ye-T4 yamahhala iphakanyisiwe, kunezibonakaliso ezinjalo:
- izinhliziyo zomzimba;
- ukuzwa ukhathazeka;
- ukuvuvukala kobuso;
- ukulahlekelwa kwesisindo;
- ubuthongo obubi obungenakuphumula;
- ukuthuthumela kwemikhawulo;
- ukugoqa kwamehlo ku- goiter enobuhlungu .
Uma isiguli sinempawu zesifo segciwane, kufanele sinikezwe ukuhlaziywa kweH4 hormone yamahhala. Kuzosiza ekutholeni noma yikuphi ukulimaza emgodini wegciwane futhi kuthathwa njengesinyathelo sokuqala sokuthola ukuxilongwa okulungile.