Ubude bezinhlelo ze-IVF buxhomeke kulokho okulungiselelwe ukusetshenziselwa ukukwenza. Kukhona umehluko esikhathini esingakanani ukuthi ubude besikhathi esifushane se-IVF protocol ngukuthi i-pituitary ivimbelwe yi-agonists noma abaphikisi be-GnRH.
Kuzoze kube nini i-protocol emfushane ye-IVF?
I-protocol emfushane kanye nokusetshenziswa kwama-agonists ka-GnRH kufanele ahlale ezinsukwini ezingu-28-35, futhi i-ultrashort esebenzisana nabaphikisi be-GnRH ithatha izinsuku ezingu-25-31 esikhathini eside.
I-protocol emfushane neyesikhathi eside ye-IVF isebenzisa amalungiselelo afanayo e-hormonal, kodwa isingeniso sabo asiqali ngomjikelezo owodwa wokuya esikhathini, kodwa siyathatha eyedlule, okuzohlinzeka inani elikhulu lamaqanda ekhwalithi. Ukuze wenze lokhu, ukuvinjwa kwe-pituitary gland kuqala ngesonto ngaphambi komjikelezo, lapho izigaba eziyinhloko ze-IVF kufanele ziqale.
Izigaba ze-IVF - protocol emfushane
Uhlelo lwe-protocol emfushane ye-IVF liqukethe izigaba ezine zokuqaliswa kwalo:
- ukugqugquzela ukuphakama okukhulu (inqubo yokugqugquzela i-ovulation in follicles eziningana zama-ovarie wesifazane);
- ukukhishwa kwama-ovari (ukukhipha ukukhishwa kwamapulisi okuvuthwa e-ovum yokukhulelwa, isimo esibophezelayo - ngaphambi kokuba kutholakale isidingo sokugwema ubulili izinsuku ezintathu);
- ukuxubha emibungu (emva kokugqama ngaphansi kwe-microscope, funda indaba, ukhethe futhi ugeze amaqanda aphelele futhi uhambise imibungu emacimbini amaningana e-zygotic, kufika kumaseli angu-4 kuya ku-8);
- Ukufakelwa kombungu esibelethweni (ngokusekelwa okuyimpoqo komsebenzi ophuzi womzimba nge progesterone nokulawula kokukhulelwa 2 amasonto emva kokufakelwa).
Uhlelo lwe-IVF ngezinsuku
Ubude besikhathi se-IVF buxhomeke kulokho okusetshenziselwa khona umthetho-isikhathi eside, esifushane noma esincane. Ngokuhamba kwesikhathi, umahluko phakathi kwabanye, ukuvinjwa kwe-hormone ye-pituitary gland kuqala kusukela ezinsukwini ezingu-21 zomjikelezo odlule, uthola inqwaba yamaqanda, kodwa ukuthuthukiswa kwengcindezi, i- ovarian hyperstimulation syndrome, kungenzeka.
Esikhathini esifushane kanye ne-ultrashort protocol, i-pituitary blockade iqala kusukela ngosuku lwesi-2-5 lwenyanga yokuya esikhathini nokuvuselela okufanayo ngesikhathi esisodwa, okugcina izinsuku ezingu-12-17 ku-protocol emfushane, kanye nezinsuku ezingu-8-12 kuphela kwi-ultrashort.
Ukuqothula ama-ovari nge-protocol emfushane ye-IVF kwenziwa ngosuku oluyi-14-20 kusukela ekuqaleni kokuvuselela, nge-ultrashort izinsuku ezingu-10-14 zokuphakamisa.
Ukutshalaliswa kombungu wezimbili zomsebenzi kwenziwa ngezinsuku ezingu-3-5 emva kokukhishwa kwe-ovarian, nokulawula ukukhulelwa - amaviki amabili emva kokufakelwa, ngenkathi ngesikhathi esifanayo kusekela umsebenzi womzimba ophuzi nama-analogs e-progesterone.