Ama-enzyme esibindi - lena enye yezingxenye ezibaluleke kakhulu izinqubo zezinto eziphilayo ezinomzimba. Njengoba isibindi senza inqwaba yemisebenzi, i-enzyme eyenziwe yiyo ihlukaniswe ngamaqembu amaningana: i-excretory, i-indicator kanye ne-secretory. Njengoba kunezifo ezihlukahlukene kanye nokulimala kwesibindi ku-plasma yegazi, okuqukethwe kwe-enzyme kuyashintsha. Lesi simo sibonakaliso esibalulekile sokuxilonga.
Yimaphi ama-enzyme ebindi asetshenziselwa ukuxilongwa?
Ama-enzyme esibindi, okukhona okungakhula ezifweni ezihambisana nokubhujiswa kwe-hepatocytes, kuthiwa yi-indicator enzymes. Lokhu kufaka:
- glutamate dehydrogenase (Gldg);
- i-aspartate aminotransferase (AST);
- i-lactate dehydrogenase (i-LDH);
- i-gamma-glutamyltransferase (GGT);
- i-alanine aminotransferase (ALT).
Ngokuvamile, izifo zesibindi zenzelwe ukuhlolwa kwegazi ngokuzimisela kokuqukethwe kwe-enzyme ye-AST ne-ALT. Kwabesifazane, umkhuba we-ACT ungama-20-40 U / l. Ngokulimala komzimba noma umonakalo kuma-hepatocytes, lezi zinzyzy zandisa umsebenzi omkhulu.
Umkhuba wokuqukethwe kwe-enzyme yesibindi i-ALT egazini ngu-12-32 U / l (owesifazane). Ngezifo ezithathelwanayo, umsebenzi wabo ukwandisa kakhulu - ngezikhathi eziningi. Kulesi simo, izimpawu zomtholampilo zingase zingekho. Yingakho i-ALT ivame ukusetshenziselwa ukuthola isifo sofuba ngesikhathi sokuqala.
Enye ithuluzi lokuxilonga yi-Rit coefficient (isilinganiso se-AST / ALT). Kumuntu onempilo, ku-1.3.
Izivivinyo ezengeziwe ze-hepatic ze-enzyme
Ukwenza ukuhlukaniswa kwezifo ezinembile ngokwengeziwe, i-laboratory ingabuye ihlolisise ukuhlaziywa futhi ikwazi ukuthola zonke izinhlobo ze-enzyme zesibindi egazini. Ezilonda ezihlukahlukene zesifo sobindi, izifo ezingokwemvelo, ubuthi obukhulu nezifo ezithathelwanayo, okuqukethwe kweGldg yesiguli (
Ingxenye ye-enzyme yesibindi ifihliwe emidayini ye-bile. Bahlanganyela ekugayeni. I-enzyme enjalo i-alkaline phosphatase. Ngokuvamile okuqukethwe kwe-alkaline komhlaba izinsimbi akumele kudlule i-120 U / l. Kodwa uma izinqubo ze-metabolic metabolic ziphulwa, le nkomba yanda cishe ku-400 U / l.