Amakhomoni we-hypothalamus

I-Hypothalamus ingenye yezitho ezisemqoka ohlelweni lwe-endocrine yomuntu. Itholakala eduze nesisekelo sobuchopho. Unesibopho sokusebenza kahle kwegciwane le-pituitary kanye nesimetabolism evamile. Ama-hormone akhiqizwa kwi-hypothalamus zibaluleke kakhulu emzimbeni. Ziyi-peptide eziphethwe izinqubo ezahlukene ezenzeka emzimbeni.

Yiziphi ama-hormone akhiqizwa yi-hypothalamus?

Ku-hypothalamus kukhona amangqamuzana omzimba, aphethwe ukukhiqizwa kwazo zonke ama-hormone abalulekile. Zibizwa ngokuthi ama-neurosecretory cells. Ngomzuzwana othile, bathola izimpikiswano zesifo sezinzwa, ezinikezwa izingxenye ezahlukene zesistimu yezinzwa. Ama-axx we-neurosecretory amangqamuzana aqeda emithanjeni yegazi, lapho enza khona i-axo-vasal synapses. Ngama-hormone wokugcina kanti ama-hormone akhiqizwayo akhishwe.

I-hypothalamus ikhiqiza ama-liberin nama-statins - okuthiwa ukukhulula ama-hormone. Lezi zinto zidinga ukulawula umsebenzi we-hormonal we-pituitary gland. Izitatimende zinesibopho sokunciphisa ukuhlanganiswa kwezakhi ezizimele, namaLiberia ngokukhuphula.

Kuze kube manje, ama-hormone afundiswe kahle kakhulu e-hypothalamus:

1. I-Gonadoliberines. La mahomoni anesibopho sokwandisa inani lama hormone ezocansi akhiqizwayo. Bamba iqhaza ekusekeleni umjikelezo ojwayelekile wokuya esikhathini nokubunjwa kwesifiso socansi. Ngaphansi kwethonya lemali enkulu ye-lyuliberin - enye yezinhlobonhlobo ze-gonadotypes - amaqabunga amaqanda avuthiwe. Uma lawa mahomoni ayanele, owesifazane angathuthukisa ukungabi nalutho .
2. Somatoliberin. La mahomoni, akhiqizwa yi-hypothalamus, adingekayo ukuze akhiphe izinto zokukhula. Kumelwe ukuba bathuthukiswe kakhulu ebuntwaneni nasebusha. Uma kungenakho i-hormone, i-dwarfism ingaqala.
3. Corticoliberin. Ubhekene nokukhiqizwa okunamandla kwamahomoni adrenocorticotropic emgodini we-pituitary. Uma i-hormone ingakhiqizwa emalini edingekayo, ezimweni eziningi ukungakwazi ukusebenza kwemvelo kuyakhula.
4. I-Prolactoliberin. Lesi sici sisebenza ngokukhethekile kufanele sithuthukise ngesikhathi sokukhulelwa nasesikhathini sokukhulelwa. Lesi sici sokukhulula sandisa inani le-prolactin elikhiqiza futhi likhuthaza ukuthuthukiswa kwamakhaya esifubeni.
5. I-Dopamine, i-melanostatin ne-somatostatin. Baqeda ama-hormone ashisayo akhiqizwa emgodini we-pituitary.
6. I-Melanoliberin. Ihlanganyela ekwakhiweni kwe-melanin nokukhiqizwa kwamaseli e-pigment.
7. ITyroliberin. Kubalulekile ukuhlukanisa amahomoni e-thyroid-stimulating futhi ukwandise i- thyroxine egazini.

Ukulawulwa kwe-secretion yama-hormone we-hypothalamus

Isistimu yezinzwa isabela ekulawulweni kwe-hormone secretion. Amahomoni amaningi i-gland ehlosiwe ikhiqizwa, ukuvinjelwa okuncane kwamahomoni ashisayo. Lobudlelwane abukwazi nje ukusebenza ngokucindezelayo. Kwezinye izimo, lishintsha umphumela wamahomoni we-hypothalamus kumaseli asegundeni le-pituitary.

Imithi ye-hormone ye-hypothalamus

Lokhu kufaka:

1. ISermorelin. I-analogue ye-hormone yokukhula yemvelo. Iphethwe ngokuyinhloko ezinganeni ezincane kakhulu. Akuvunyelwe ngesikhathi sokukhulelwa nangesikhathi sokukhulelwa.
2. I-Bromocriptine. Isetshenziselwe ukukhuthaza i-postsynaptic dopamine receptors. Lunqunyelwe ukuphazanyiswa kwe-lactation.
3. Okreotid. Kunganciphisa ukukhiqizwa kwamahomoni okukhula kanye nokucindezela umsebenzi wezicubu ezinamahloni. Iyalwe izilonda kanye nezicubu zokufihla.
4. Rifatiroin. I-analogue yehomoni ye-hypothalamus ye-tiropropin.
5. I-stylamine. Kunganciphisa ukugeleza kwegazi ezingxenyeni zangaphakathi, ngaphandle kokuphazamisa ukucindezela kwegazi ohlelweni.