I-Enam ibhekwa njengenye yezidakamizwa ezinamandla kunazo zonke nezingazingeni eliphezulu. Izinkomba zokusetshenziswa kwe-Enam zilinganiselwe, ngoba ikhambi lithathwa njengokugxila kancane. Kungenxa yalokhu ukuthi umuthi awusebenzi nje kuphela, kodwa futhi usebenza.
Indlela yokusebenza ka-Enam
Into esebenzayo enkulu ekulungiseleleni i-enatepril maleate. Yilesi sigaba, ukungena emzimbeni, kuhlanganiswa futhi kuguquke ibe yinto ephumelelayo nangokwenza ngokushesha-i-enalaprilat.
Ngaphezu kwe-enalapril, u-Enam uqukethe izingxenye ezilandelayo:
- i-zinc stearate;
- i-maleic acid;
- i-lactose anhydrous.
Isidakamizwa senza kalula: ngemuva kokukhululwa kwe-enalaprilat, umzimba uvimbela ukukhiqizwa kwama-enzyme angiotensin. Ngenxa yalokhu, ukuguqulwa kwe-angiotensin I nge-angiotensin II kuvinjelwe. Futhi-ke, ukuphikisana kwemiphakathi jikelele kwezemikhumbi kunciphisa, ukucindezela kwe-systolic kanye ne-diastolic kunciphisa. Inzuzo enkulu ye-Enam yukuthi ukusetshenziswa kwayo akuthinti ukuthuthukiswa kwe- tachycardia ye-reflex nganoma iyiphi indlela.
Iveza imithi neminye imiphumela:
- kuqinisa ukujikeleza kwegazi ezintsheni;
- kusebenze izinhlelo zokucindezeleka;
- izinhlelo zokucindezela ezicindezelayo;
- kunciphisa ukuxhunywa kwe-ventricular kwesokunxele;
- kunciphisa kakhulu isidingo se-carbohydrate e-oxygen;
- ithuthukisa isimo sensimu yenhliziyo ne-hypoxia.
Kubalulekile ukuqaphela ukuthi ukungena kwe-Enam akuthinti i-lipid ne-carbohydrate metabolism. Kwezinye izigaba zeziguli, le nqubo yokukhetha imithi ingenye ebaluleke kakhulu.
Kungakhathaliseki ukuthi kuthathwa amaphilisi e-Enam, baqala ukwenza amaminithi ambalwa ngemva kokungenisa. Ukuhlushwa okukhulu kwe-enalaprilat emzimbeni kufinyelelwa emahoreni amathathu kuya kwangu-4. Ukususwa kwezingxenye eziyinhloko ze-Enam kufana nezinso. Umzimba uhlanza ngemuva kwamahora angu-11-12.
Izinkomba eziyinhloko zokusetshenziswa kwe-Enam
I-Enam ingenye yezidakamizwa ezinamandla ochwepheshe abangasincoma ukuthi basebenzise abangalawuliwe. Isiboniso esiyinhloko sokusetshenziswa kwe-Enam - ekucindezelekeni okuphakeme. Muva nje, inani elikhulayo labodokotela liye lakhetha ukwelashwa kwesifo somfutho wegazi ophezulu ngale mithi. Amandla ka-Enam nawo amanga eqinisweni lokuthi ikuvumela ukuba ulwe nezinhlobo ezehlukene zomshukela ophezulu, kuhlanganise nalabo abane-hypertension ebalulekile yokuvuselela umzimba.
Isidakamizwa siye sazibonakalisa ekwelapheni kwezifo ezinjengalezi:
- ukuhluleka kwenhliziyo engapheli ;
- i-ischemia ye-coronary.
Ukulwa nalezi zinkinga, i-Enam ingasetshenziswa njengokwelashwa okuzimele, kodwa ngokujwayelekile umuthi uba yingxenye yokwelashwa okuhlangene.
Ukuzivocavoca kugcizelele ukusebenza kahle kwemithi njengendlela yokuvimbela izifo ezichazwe ngenhla.
Ukungahambisani nokusetshenziswa kwe-Enam
Imithi yokuphatha ngomlomo ihloselwe. Umthamo wansuku zonke ophezulu ka-Enam ungama-40 mg. Sebenzisa lesi sidakamizwa sinconywa kanye ngosuku, kungakhathaliseki ukudla ukudla.
Njengazo zonke izidakamizwa, u-Enam akafanelanga zonke iziguli. Isidakamizwa sokuphikisana lapho:
- i-aortic stenosis;
- ukukhulelwa;
- ukuncelisa;
- kungenzeka ukuthi ukuthuthukiswa kwe-angioedema ngemuva kwendlela yokwelashwa nge-ACE inhibitors;
- ukubekezelelana ngabanye izingxenye zomuntu ngamunye.
Ngokuqapha okukhulu, u-Enam udinga abantu abanezifo ezinjalo:
- i-hypovolemia;
- ukwephulwa kwemali yamanzi usawoti;
- ukuqina kwesifo se-renal;
- i-syndrome ye-malabsorption ye-glucose-galactose.