I-bile yiketshezi eluhlaza okwesibhakabhaka elimnyama eligcinwe ngamaseli wesibindi (hepatocytes) ngokuqhubekayo.
Ubuningi be-synthesized bubutha emadayeni we-bile, futhi ukusuka lapho ungena enkongweni ye-gallbladder ne-duodenum, lapho kuthatha ingxenye esebenzayo kwinqubo yokugaya. Uma nje i-bile ihamba emathunjini, iningi lalo liyasondla izakhi, kanti konke okususwa emzimbeni kanye nendwangu.
Uma imisebenzi yokwakhiwa kwe-bile nganoma yisiphi isizathu iphulwa, khona-ke isibindi nesifo se-gallbladder sokuvuvukala siyagula, ngaphezu kwalokho, ukugaya kuyaphela. Kulesi simo, misela amalungiselelo okukhetha, uhlu kanye nokwahlukaniswa okufakwe ngendlela ekhishiwe, sizozama ukwethula ngezansi.
Izidakamizwa ze-cholagogue
Ukuhlukanisa ukuhlunga okushoyo:
- imvelaphi yemvelo (i-artichoke ithole, i-tansy, izimpande ze-burdock, ama-corn stigmas, izimpande ze-dandelion, amaqabunga enambuzane, i-immortelle, njll);
- isakhi.
Ngokwendlela yokusebenza (i-pharmacodynamics), ukuhlukaniswa kwamalungiselelo e-cholagogue wamanje kuningi kakhulu, kodwa konke kungahlanganiswa ngamaqembu amabili:
- Choleretics - qinisa ukwakheka kwe-bile acid (LC) ne-bile.
- I-cholekinetics ne-cholespismolytics - zithuthukisa i-excretion ye-bile ku-duodenum ngokugqugquzela ukuchotshozwa kwe-gallbladder noma ngokuphambene nokuphumula i-sphincter ye-Oddi kanye nemisipha ye-bile ducts.
Lokhu kuhlukaniswa kunemibandela, ngoba iningi lamalungiselelo asebenza kahle e-cholagogue ngokulinganayo alithuthukisa kokubili ukuhlanganiswa nokuvinjelwa kwe-bile.
I-Choleretics
Leli qembu lemithi ye-cholagogue, futhi, linalolu hlobo olulandelayo.
I-choleretics yeqiniso yizidakamizwa, okucacile okuzokwandisa ukwenziwa kwe-bile ne-lactic acid. Le mithi inga:
- aqukethe i-LCD ngqo (Holenzim, Allochol, Vigheratin, njll);
- yenza izinto zokwenziwa (Nikodin, Oxafenamid, Tsikvalon, Odeston, njll);
- unemvelaphi yemvelo (iTanachevol, Holosas, Flakumin, Convaflavin, njll);
I-Hydrocholeretics yizidakamizwa ezandisa ukwenziwa kwe-bile ngamaseli esibindi ngenxa yamanzi. Kuleli qembu, amalungiselelo amahle kakhulu e-cholagogue amelwa ngamanzi amaminerali (Jermuk, Essentuki No. 17, No. 4, Izhevskaya, njll), i-salicylate ye-sodium nemikhiqizo e-valerian.
Ukulungiswa kwaleli qembu kunqunywe izifo zesibindi ezingapheli; ukwephula ukuphuma kwe-bile (i-dyskinesia ye-bile ducts). Uma kunesidingo, lezi zidakamizwa zihlanganiswa nama-antibiotics, ama-laxatives, ama-analgesics.
I-Cholekinetics ne-choleospasmolytics
Ezintweni, umphumela wawo ohlinzeka ukwanda kwethembo le-gallbladder kanye namathanga (cholekinetics), faka:
- i-magnesium sulfate;
- cholecystokinin;
- amalungiselelo asekelwe barberry ;
- i-mannitol;
- i-choleritin;
- i-pituitrin;
- i-sorbitol;
- xylitol.
Lezi zilungiselelo ze-cholagogue zikhonjiswe nge-cholecystitis engapheli, ukwephula ukuphuma kwe-bile (dyskinesia), i-atony ye-gallbladder, isifo sofuba esingapheli.
Izinto ezithobisa imisipha ye-bile duct (holespazmolitiki):
- i-platyphylline;
- i-atropine;
- i-iodide ye-metocinium;
- ukukhishwa kwebladladonna;
- aminophylline;
- i-papaverine;
- i-drotaverine;
- i-mebeverin;
- i-olimethine.
Leli qembu lamalungiselelo e-choleretic liphumelela ku-cholelithiasis ne-dyskinesia yefomu le-hyperkinetic.
Qaphela
Bhala ukuthi imithi efakwe ohlwini kufanele ibe yedwa udokotela, njengoba isenzo sabo sihlukile. Amalungiselelo okugcoba ama-giardiasis, ngokwesibonelo, futhi nge-pancreatitis, cholecystitis , i-hepatitis izohluka. Ngakho-ke, ukuzivocavoca kungabangela kakhulu isithombe sesifo.