I-Hyperandrogenism isimo somtholampilo womzimba wesifazane uma kune-overabundance ye-sex hormones androgens (testosterone) yesilisa. Umzimba wesifazane ngobuncane obukhiqiza leli hormone yi-adrenals nama-ovaries. Kuyadingeka ukuthi ukusebenza okujwayelekile kwemisipha ye-myocardium kanye nokuthuthukiswa kwemisipha yamathambo.
Nokho, uma i-testosterone ikhiqizwa ngokweqile ngokweqile, lokhu kuholela ekuthuthukiseni i-syndrome ye-hyperandrogenism. Lesi sifo sibhekisela ekuphazamiseni uhlelo lwe-endocrine.
I-Hyperandrogenia - izimpawu
Izimpawu zangaphandle ze-hyperandrogenism zanda ukwanda kwezinwele ezandleni, emilenzeni nasebusweni. Ebusweni kaningi kungaba khona ukuqhuma kwamaphambo ngisho nokuvuvukala. Kodwa-ke, ungadideli i-hyperandrogenism ngokuzwela okukhulu kwe-androgen, ehambelana nabesifazane abaningi ezindaweni eziseningizimu. Lokhu kubangelwa ukwanda kwezinwele kanye nezinye izimpawu kubesifazane abavela kuleli qembu lobuhlanga.
Nge-hyperandrogenism yeqiniso, le nkinga ijulile futhi ithinta izinqubo ze-metabolic eziphulwa, okuholela engozini yokuthuthukisa isifo sikashukela nokukhuluphala. Izimpawu zangaphakathi ze-hyperandrogenism zingama- cysts amaningi emaqanda ama-ovari (polycystosis) , okuholela ekuphukeni komjikelezo wokuya esikhathini, ukuvuthwa futhi ekugcineni kuholele ekusaneni.
Futhi uma owesifazane esakwazi ukukhulelwa, ngokuvamile kuphelelwa isisu. Lokhu kungenxa yokukhiqizwa okunganele kwe-hormone yesine, i-progesterone. Uma ukukhulelwa kugcinwa futhi icala lifika ekulethwa kwezidingo, khona-ke zingakwazi ukuhambisana nokukhishwa kokuqala kwe-amniotic fluid, umsebenzi ongasebenzi okwanele. Konke lokhu kungabonakaliswa nezimpawu ze-hyperandrogenism.
Izimbangela ze-hyperandrogenism
Isifo esiyinhloko salesi sifo ngu-testosterone. Futhi njengoba ikhiqizwa yi-adrenal and ovaries, imbangela ye-hyperandrogenism kwabesifazane ukuphazanyiswa komsebenzi walezi zitho.
Isizathu esiyinhloko sibizwa ngokuthi i-androgenital syndrome. Ezingqungqutheleni eziyingozi, amahomoni amaningi akhiqizwa, kuhlanganise ne-testosterone. Futhi ngaphansi kwesenzo se-enzyme ekhethekile ye-ovaries testosterone namanye ama-hormone aguqulwa abe yi-glucocorticoids. Futhi uma kungekho ama-enzyme anele kuma-ovari, ukuguqulwa kuyeka futhi i-testosterone iqala ukuqoqa emzimbeni.
Esinye imbangela yalesi sifo ukukhiqizwa kwe testosterone emaqanda ngokwabo. Futhi imbangela ehlukile ihluke izicubu emaqanda nama-gland adrenal.
Yiqiniso, uhlelo lwe-endocrine luhlanganisa nezinye izitho. Futhi ukwephula emsebenzini wabo kungabangela nasekuthuthukiseni ama-hyperandogens.
I-Hyperandrogenism - Ukuxilongwa Nokuphathwa
Ukuxilongwa kwe-hyperandrogenism kusekelwe ekuhlaziyeni okuthile, ukuhlolwa kwe-ultrasound, ukucaciswa kwemininingwane yokukhulelwa kanye nokubonakaliswa kokuqala kwalesi sifo nokuthola ukuxhumana phakathi kwalezi zenzakalo. Izimpawu zalesi sifo zingabonakala kunanoma yisiphi isikhathi, ngakho kunzima ukukhuluma ngeminyaka yobudala noma ukuzalwa komuntu.
Ukwelashwa kwe-hyperandrogenism ngokuqondile kuxhomeke kwizimbangela zokubonakala kwayo, kanye nemigomo. Uma ukwelashwa kuqalwa ngenxa yokukhulelwa, akwanele ukuqeda ukubonakaliswa kwangaphandle kwesifo.
Uma ihlotshaniswa nokwakheka kwezidumbu, khona-ke zisuswe ngokuhlinzwa. Uma lesi sifo siholele ekukhulupheni, khona-ke ngaphezu kokwelashwa kwendabuko, udokotela uzokwenza ukuthi imishanguzo ibuyele kwisisindo sangaphambilini.
Ukunakekelwa kwabesifazane, bebhekene nale nkinga, namuhla iphathwa ngokuphumelela okukhulu. Awukwazi nje ukukhipha ukubonakaliswa kwangaphandle okungalungile, kodwa futhi ube nethuba lokubeletha umntwana.