Njengoba wazi, ngesikhathi sokukhulelwa emzimbeni wesifazane kukhona izinguquko eziningi ezithinta umsebenzi cishe zonke izitho nezinhlelo. Igazi akuyona into ehlukile.
Ngaphansi kwethonya lenani elikhulu lama-estrogens egazini labesifazane abakhulelwe, uhlelo lwe-homeostatic luhlale lukhona "isimo sokuqapha". Leli qiniso liboniswa ngqo ekuhlaziyeni: inani le-fibrinogen egazini, i-prothrombin ne-antithrombin iyanda. Ngakho-ke, ngokuvamile owesifazane unqunywe ukuhlaziywa kwe-D-dimer ukuze uhlole amanani ngendlela evamile noma kukhona ukwehluka.
Kuyini "D-dimer"?
Lokhu kuhlaziywa kusivumela ukuthi sinqume ukuhlushwa egazini lemikhiqizo yokulimaza ye-fibrinogen, ehlanganyela ekucubunguleni. Yebo. i-D-dimer ephezulu ibonisa ukuthi umzimba wesifazane okhulelwe ujwayele ama-blood clots.
E-EU, le ndlela ngokuvamile isetshenziselwa ukukhipha ubukhona be-thrombosis. Ngakho-ke, uma izindinganiso zalolu cwaningo ziyancipha noma zingaphansi kobubanzi obuvamile, kungaba ngu-100% ukuthi kungenzeka ukuthi i-thrombosis ayiyona imbangela yokuthuthukiswa kwesimo esiphuthumayo esiphuthumayo. Ngakho-ke, ngokuvamile, i-D-dimer isetshenziselwa ukuvuselelwa, uma isikhathi sibaluleke kakhulu.
Isilingo se-D-dimer senziwa kanjani?
Lokhu kuhlaziywa akufani nalokho okujwayelekile kwesampuli segazi kusuka emthanjeni. Ngaphambi kokuthatha i-D-dimer, amahora angu-12 ngaphambi kokuvinjelwa ukuba adle, futhi ukuhlaziywa kwenziwa kuphela esiswini esingenalutho.
Igazi eliqoqiwe lihlaziywa ngokucophelela kwamakhemikhali ngokusebenzisa izinkomba ezikhethekile ezikhomba ukutholakala noma ukungabikho kwemikhiqizo ye-fibrinogen progradation. Ngokuvamile akudingi ngaphezu kwemizuzu engu-10-15 ukuthola umphumela, okwenza kube lula ukuthi lolu hlobo locwaningo lubonise ukuhlolwa.
Amanani kaD-dimer kubantu abanempilo
Ngokuvamile, ukujwayelekile kukaD-dimer kwabesifazane abangabhalanga izingane kuyahlukahluka phakathi kuka 400-500 ng / ml. Futhi ilokhu ishintsha njalo, futhi ixhomeke esigabeni somjikelezo wokuya esikhathini. Ngaphezulu kuka 500 ng / ml ukukhuluma ngokuthuthukiswa kwe-pathology.
Amanani kaD-dimer ekukhulelwe
Umkhuba kaD-dimer ngokuqondile uxhomeke esikhathini sokukhulelwa kanye nokuguqulwa kokuqala kwe-trimester elandelayo. Ngakho ngokuvamile ku-trimester yokuqala lesi sibonakaliso sanda izikhathi ezingu-1.5 futhi singathatha inani elilingana no 750 ng / ml. Ngokuqhubeka nokwanda kwesikhathi, inani libuye lishintshe ohlangothini olukhulu.
Ngama-trimester amabili ama-D-dimer amanani angakwazi ukufinyelela ku-1000 ng / ml, futhi ekugcineni kwethemu - ukwanda ngezikhathi ezintathu uma kuqhathaniswa nomkhuba, - kuze kufike ku-1500 ng / ml.
Uma izindinganiso ze-D-dimer zidlula lezi zimiso, khona-ke zikhuluma ngokulandelana kwe-thrombosis.
Amanani kaD-dimer ku-IVF
Ezimweni eziningi, i- IVF yenziwa ngenqubo yokuqothulwa kwemvelo, okuholela ekwandeni kwama-estrogens egazini. Ukwanda kwabo kungabangela ukuthuthukiswa kwe-thrombosis kwabesifazane. Ngakho-ke, ukuhlolwa okuqhubekayo kwegazi ku-D-dimer, okukuleli cala kudlala indima yemakaki, kubaluleke kakhulu.
Ngokuvamile, ngemva kwe-IVF ephumelelayo, isilinganiso esithile sezinga le-D-dimer siyaziwayo. Kodwa-ke, izindinganiso zalo zifaniswa nalabo abayisici segazi labesifazane abakhulelwe ngokwemvelo.
Ngakho-ke, ukuhlaziywa ku-D-dimer kuyindlela enhle kakhulu yokucwaninga kwelabhutrikhi, okuzoqeda ngokuphelele ukuthuthukiswa kwe-thrombosis, edinga ukwelashwa okusheshayo futhi ngokuvamile iholela ekuthuthukiseni izimo eziphuthumayo. Ngakho-ke, wonke owesifazane okhulelwe kumele athathe lokhu kuhlaziywa, okusiza ekuboneni ukwephulwa kwesistimu yokugubha igazi .