Ngezizathu ezingacacisiwe, i-bile ducts ingashiswa ngokunciphisa okulandelayo, okuholela ekuhlanganiseni okungunaphakade kwe-bile. Lesi simo, esiyinhloko se-sclerosing cholangitis, sibhekwa njengesimo se-autoimmune, njengoba kuvame ukuhambisana ne-pathologies efana nesifo sikashukela, i- ulcerative colitis , thyroiditis.
Izimpawu ze-primary sclerosing cholangitis
Ukubona i-syndrome echazwe ekuqaleni kwezinyathelo cishe akunakwenzeka, ngoba iqhubeka isikhathi eside ngaphandle kwempawu ebonakalayo. Isithombe sesitholampilo sibonakala ngisho nangesikhathi sokuthuthukiswa kwe-cirrhosis yesibindi noma i-portal hypertension:
- ukhathala okwandayo;
- itching;
- isisindo somzimba esinciphile;
- ubuhlungu nobukhulu ku-hypochondrium enhle;
- ukuphuza ngezikhathi zesikhumba (i-transitory jaundice);
- ukuwohloka kwesifiso;
- okungavamile - umkhuhlane.
Ukuxilongwa kwe-primary sclerosing cholangitis
Ukuqinisekiswa kokusola kwesifo esibucayi, ngaphezu kokuqoqwa komlando nokuhlolwa komtholampilo, kwenziwa ngosizo lwezifundo ezilandelayo ze-instrumental kanye ne-laboratory:
- i-biochemical, i-immunological analysis of blood;
- i-cholangiography;
- isibindi sesibindi;
- ukuzwakala kwe-duodenal;
- i-elastography yesibindi;
- ukubuyisela kabusha i-pancreatocholangiography;
- FEGDS.
Ukwelashwa kwe-primary sclerosing cholangitis
Ukuphulukiswa ngokuphelele kwe-pathology akunakwenzeka, ukwelapha izidakamizwa kuhloswe ukunciphisa ukuqhubeka kwe-cholangitis nokuthuthukisa isimo sesiguli. Kuhlanganisa izidakamizwa ezilandelayo:
- antispasmodics;
- ama-hormone e-glucocorticosteroid;
- immunosuppressors;
- ama-antifibrogenic agents;
- ama-enzyme okugaya;
- i-hepatoprotectors ;
- izidakamizwa ezisuselwa ku-ursodeoxycholic acid.
Ngaphezu kwalokho, ama-antihistamine anganconywa ukuze anciphise i-pruritus.
Uma ukuvinjelwa kwama-bile amadokhumenti nokungahambi kahle kokwelashwa okunomsoco, ukuhlinzekwa okuhlinzekwa kokufakelwa kwesibindi kunqunywe.