Ingubo ye-thyroid iyinhlangano enkulu kunazo zonke emzimbeni womuntu. Awekho amakhodi kuwo, ngakho wonke ama-hormone awakhiqiza ngaso sonke isikhathi, ngokushesha awela egazini. I-gland yegciwane ilawulwa yi-hypothalamus ne-pituitary gland. Kuzo ukuthi ama-hormone adingekayo ukuze asebenze ngendlela evamile yohlelo lonke lwe-endocrine akhiqizwa.
Yini ethinta i-hormone ye-TSH?
I-TSH (i-thyrotropic hormone) yi-hormone elawulayo yobuchopho bomuntu. Ikhiqizwa ku-lobe yangaphakathi ye-pituitary gland futhi ilawula umsebenzi wegciwane le-thyroid. I-Thyrotropin yenza ama-receipt gland, futhi lokhu kwandisa inani nobukhulu bamaseli wegciwane. Kodwa akusikho konke, okuhlangana khona i-hormone i-TTG. Futhi:
- ivuselela i-adenylate cyclase;
- ukwandisa ukungena kwe-iodine ye-thyroid ngamaseli;
- ukwandisa ukuhlanganiswa kwamaprotheni, ama-phospholipids nama-acid nucleic.
Kodwa okubaluleke kakhulu, lokho kuthinta i-hormone TSG - ukukhiqizwa kwe-hormone ye-thyroid T4 kanye ne-hormone ye-bi-active ebizwa nge-TZ. Nguye ovuselela ukubukeka kwawo, futhi kubaluleke kakhulu ekusebenzeni okujwayelekile kwenyama yonke, ngoba i-T3 ne-T4 yenza imisebenzi enjalo:
- ukusheshisa ukucabanga;
- Ukwandisa umsebenzi wemoto nokucindezelwa kwegazi;
- sigcine isikhungo sokuphefumula;
- ukwandisa imvamisa kanye namandla okuphambana kwesigqi senhliziyo;
- ukwandisa umsebenzi wengqondo;
- ukugqugquzela ukufaniswa kwamaprotheni okwakhiwa kwe-hormone ye-renal;
- ukusheshisa ukungena kwe-oksijini ezingxenyeni.
I-hormone TSH emzimbeni
Kukhona ubudlelwane obuphambene phakathi kwezingxube ze-hormone TSH ne-T4 yamahhala. Uma kune-thyroxine eningi (i-T4) egazini, lokhu kuholela ekunciphiseni okubukhali ekukhiqizeni i-hormone ye-hormone ehehayo ye-thyroid. Ngakho-ke, ukwehla kwe-T4 ukugxila kwandisa ukukhiqizwa kwe-TSH. Ukwehlukana okujwayelekile kungabonisa ukuba khona kwezifo emzimbeni futhi kubangele ukuthuthukiswa kwamathambo.
Ngakho-ke, uma i-hormone ye-TSH iyancishiswa, kungenzeka ukunciphisa umsebenzi we-pituitary gland kanye nokuvela kwe- hyperthyroidism , futhi i-TSH eyengeziwe ibonisa ukungabi nokusebenza okunamandla kanye nokuba khona kwezifo ezinzima ezingqondweni noma izicubu. Ukunciphisa kwe-T4 noma i-T3 kungabangela:
- ukuvela kwe-edema;
- ukwehlisa amandla amakhono;
- ukunciphisa ukucindezelwa kwegazi;
- ubuhlungu enhliziyweni ;
- ukuphazamiseka kwenhliziyo;
- izinkinga zesistimu yokuzala;
- ukuphazamiseka kwepheshana lokugaya.
Kulaba besifazane abakhulelwe, ukwehlisa ukuvikeleka kwe-T3 no-T4 kungabangela ukuphazanyiswa kokubunjwa kwamasaka omntwana namaseli wesistimu yayo yezinzwa, futhi kuholele ekutheni kufaneleke ukufana kwe-oksijeni kanye nezakhi ezihlukahlukene ezingxenyeni ze-fetus.
Ukuhlaziywa kwamahomoni TTG, T3, T4
Ukuze uthole ukuhlolwa okuphelele kwegciwane le-thyroid bese ukhetha ukwelashwa okwanele, uhlaziyo oluyinkimbinkimbi lwenziwa amahomoni T4, TTG no-T3. Wonke ama-hormone we-thyroid shchitovidki angaba sezingeni elixhunyiwe noma elivulekile, ngakho-ke lokhu kuhlolwa kwegazi kungaba:
- I-T3-inani (i-triiodothyronine yamahhala) eboshwe);
- I-T4-free (thyroxine yamahhala, engahlotshaniswa nama-proteine egazi);
- I-T4-jikelele (free thyroxine + eboshiwe);
- I-TZ-free (i-triiodothyronine yamahhala (T3), engahlanganiswa nama-proteine egazi).
Izindinganiso ezivamile zokuhlushwa kwe-thyroid ye-hormone thyrogens i-TSH, i-T3 ne-T4 egazini ingase ibe nokungafani okuncane kuye ngokuthi indlela ye-laboratory esetshenzisiwe, ubudala nobulili besiguli.
Kulula ukudlula ukuhlaziywa okunjalo. Kuyadingeka kuphela:
- Qiniseka ukuthi phakathi nenyanga edlule awuthathi izidakamizwa ezithinta umsebenzi we -roid.
- Ungadli amahora angu-10-12 ngaphambi kokuhlolwa.
- Ungabhemi noma uphuze utshwala, futhi unciphise umzimba ngosuku olwandulela isifundo.