I-PUVA-therapy iyindlela ehlukile yokuphatha izifo zesikhumba ezihlukahlukene. Ingqikithi yayo ihlala emthethweni ohlangene esikhumbeni semithi yokwelapha esivela emvelweni (psoralenov (P) kanye nemisebe yelanga ende elula yomswakama we-ultraviolet.
Izinkomba zokwelashwa kwe-PUVA
Ngokuvamile ukuphathwa kwe-PUVA kusetshenziselwa i-psoriasis yezinyawo nezintende zezandla. Le ndlela yokwelapha iphumelela ngokuphumelelayo nalesi sifo, ngisho noma iziguli zihlulekile ukuqhuba izifundo ze-BUF-therapy. Ukwelashwa kwe- psoriasis nge-PUVA-therapy kungenziwa ezimweni lapho umuntu enefomu eline-drop noma eqhubekayo yalesi sifo. Phakathi nezinqubo, ukuphindaphinda kwamaseli okwenza isici sokuqhaqhazela kuvinjelwe ngokuphelele, futhi ekugcineni ukuthuthukiswa kwamacwecwe kumiswe okwesikhashana, futhi ekugcineni kuyanyamalala.
Izinkomba zalendlela yokwelashwa nazo ziyi-atopic dermatitis ne-mushroom mycosis. I-PUVA-therapy nayo inconywa nge-vitiligo. Kuzoba usizo ngisho nalabo abagulayo abanesifo esithintekile ngaphezu kwengu-20-30% yesikhumba.
Ukuphathwa kwe-PUVA akukwenziwa ekhaya. Zonke izinqubo zenziwa kuphela ngesineke (ngeziguli ezivamile noma ezikhethekile zokwelapha izifo zesikhumba). Izidakamizwa ezithathwe ngomlomo, noma ezisetshenzisiwe ngezihloko, futhi ngemva kwamahora angu-2-3 ezithintekile yizindawo zokugula zivezwe emisebeni ye-ultraviolet. Isikhathi se-irradiation siqala imizuzu embalwa, kodwa sikhula ngeseshini ngayinye. Iningi le-PUVA yokwelapha liqukethe izikhathi ezingu-10-30.
Ukuqhathaniswa nokwelashwa kwe-PUVA
I-PUVA-therapy inomsebenzi ophezulu (85%), futhi izimpawu zokuqala zokuguqulwa kwezibonakaliso zesikhumba zibonakala emva kwezinqubo ezingu-4-6. Le ndlela yokwelashwa ibekezelela kahle iziguli futhi ayilona umlutha. Nokho, akuwona wonke umuntu ongayisebenzisa.
Ukuphikisana nokuphathwa kwe-PUVA yilokhu:
- hypersensitivity kuya psoralen;
- i-melanoma enonya;
- i-lupus erythematosus ;
- aphakia;
i-pigment xeroderma; - i-albinism;
- i-porphyria;
- ukukhulelwa.
Ngokucophelela sebenzisa le ndlela ukuze uphathe iziguli ezinesikhumba esilula, izilonda, uremia nokuhluleka kwezinso. Futhi, ungasebenzisi ukwelashwa kwe-PUVA kulabo abaye bacindezeleka, noma kumuntu oye waba nezicubu ezimbi. Izifo ezimbi ze-myocardial nezinye izifo eziningi ezingavumeli isikhathi eside ukuma, kuvame ukuvimbela ukuhamba kwendlela yokwelapha ephelele.