Ukuhlaziywa kwama-antibodies ku-peroxidase ye-thyroid namuhla kubhekwa njengenye yezinto ezithandwa kakhulu. Odokotela bawabeka iziguli zabo ngokuphindaphindiwe kaningi. Ukuqonda ukuthi kusho ukuthini le nkhomba nokuthi kungani ama-antibodies ekukhuleni kwe-TPO, kuyancipha lapho uthola imiphumela yokuhlolwa.
Ubani ukuhlaziywa kwama-antibodies ku-TPO?
Lokhu kuhlaziywa kunokwethenjelwa kakhulu kunezinye izifundo eziningi ezikwazi ukubona ukuthi umzimba udala isifo esizimele noma cha. Ukukhuluma ngokucacile, isibonakaliso se-antTPO sivumela ukudalula, ukuthi isimiso somzimba sokuzivikela sinobudlova kanjani ngokuphathelene nomzimba. I-TPO inesibopho sokwakheka kwe-iodine esebenzayo, engayifaka i-thyroglobulin. Futhi amasosha omzimba avimbela lokhu, okuholela ekunciphiseni kwamakhemikhali e-thyroid.
Thumela zonke iziguli ukuhlolwa kwegazi lonke nge-antibodies ku-TPO ukuze uthole ukuthi azikhulisiwe, akulungile. Ucwaningo luboniswa kuphela ngaphansi kwezimo ezithile:
- Usana olusanda kuzalwa. Zivivinywa kuma-anti-TPO, uma lezi zinhlobo zomzimba zitholakala emzimbeni womama, noma nge-postpartum thyroiditis.
- Iziguli ezine-gland enegciwane elikhulisiwe.
- Abantu bathola i-lithium ne-interferon.
- Abantu abane-hypothyroidism. Ucwaningo luyadingeka ukuze uthole ukuthi kungani imbangela yalesi sifo.
- Ngokwezinto ezithathwa njengefa. Uma esinye sezihlobo sinezinkinga ngenxa yamagciwane okukhuphuka e-TPO, isiguli sizitholela eqenjini eliyingozi futhi sidinga ukuhlolwa okuvamile.
- Emva kokukhulelwa kwesisu. Ngezinye izikhathi izifo ezingenalo ukubeletha noma ukuzalwa okungakahlelwa ngaphambi kokuzalwa kungenzeka ngoba isimiso somzimba samasosha omzimba senza ama-antibodies aqondile.
Iyini izinga elandayo lama-antibodies ku-TPO kubonisa?
Ukubonakala kwama-antibodies ku-TPO kubonisa ngokuyinhloko ukuthi amangqamuzana wegciwane le-thyroid ayaqedwa kancane kancane, futhi inani elincane le-enzyme edingekayo likhiqizwa emzimbeni. Kunezinye izincazelo:
- Ukwanda kancane kwamagciwane okulwa ne-TPO kungahle kwenzeke ngokungahambi kahle okuzenzakalelayo: isifo samathambo , isifo sikashukela, i-vasculitis yesistimu kanye ne-lupus erythematosus.
- Uma ama-antibodies e-TPO akhuphuka kwabesifazane abakhulelwe, lokhu kusho ukuthi ingane ingathuthukisa i-hyperthyroidism cishe ngamaphesenti angama-100%.
- Ezigulini ezinama-antibodies kuya ku-TPO ukwanda izikhathi ezingu-10, i-goiter eyingozi noma i- Hashimoto's thyroiditis eyingozi kakhulu.
- Inani elikhuphuka lama-antibodies ku-TPO ekuhlaziyweni okwenziwe ngemuva kokudlula kwendlela yokwelashwa kubonisa ukungaphumeleli kwendlela yokwelashwa ekhethiwe.
Ngezinye izikhathi izifo zamagciwane ezibizwa nge-TPO zingakhula futhi azikho isizathu esicacile. Kungenzeka ikakhulukazi emzimbeni wesifazane, futhi uchazwa, njengombandela, ngokushintsha okuhlobene neminyaka. Kulokhu, lo mcimbi ubhekwa njengokujwayelekile. Kodwa ngokuhamba kwesikhathi isiguli sisatuswa isikhathi esithile ukuba sigcine isazi.
Ukwelashwa kwama-antibodies ephakeme ku-TPO
Qinisekisa ukuthi isibonakaliso senyukile, into esemqoka ngesikhathi. Inkinga yukuthi awukwazi ukuphulukisa ama-antibodies aphakeme ku-TPO. Lesi sibonakaliso singashintshwa kuphela uma kukhona okwenziwe ngesifo esenza sikhule. Uma kungekho zinyathelo ezithathwe, lesi sifo singakhula ngaphandle kokuvimbela, futhi inani lamakhemikhali athile landa.
Isigaba sokuqala sokwelapha ukuhlolwa okuphelele ukucacisa imbangela yokunyuka kwenani lama-antibodies ku-TPO. Odokotela abaningi kakhulu baphendukela ekwelashweni kwe-hormone replacement. Ukusetshenziswa kwalendlela kuyanconywa kuphela uma imbangela yenkinga isendleleni yegciwane.