I-Anaprilin yisidakamizwa esivela eqenjini le-beta-blockers elibonisa izidakamizwa ze-antianginal, hypotensive ne-antiarrhythmic. Lena imithi ephumelelayo, engabizi futhi engabizi kakhulu enganciphisa ngokushesha izinga lokushaya kwenhliziyo nokucindezela kwegazi, ukuqeda ukuhlaselwa kwesibindi, nokunciphisa isimo kwezinye izifo. Kodwa-ke, le mithi ayinayo imiphumela emibi futhi ingasetshenziswa kuphela ngaphansi kokuqondiswa kukadokotela, futhi kwezinye izimo iyaphikisana nokusetshenziswa. Ingabe zikhona izilinganiso ze-Anadrilin ngaphandle kwemiphumela emibi, futhi yimuphi ukusebenza kwazo, sizocubungula phambili.
Ama-analogues e-Anaprilin
Isidakamizwa esixoxwa njengezithako ezisebenzayo siqukethe i-propranolol hydrochloride. Ama-analogues ezinhlobonhlobo (ama-synonyms) e-Anaprilin, aqukethe into esebenzayo efanayo, imithi elandelayo:
- I-Propranolol;
- Obsidan;
- Noloten;
- I-Stobetin;
- I-Propamine;
- Propranolobene;
- I-BetaCap TR.
Njengoba imikhiqizo efakwe ohlwini ifana nokubunjwa, ngakho-ke, ngokusho kwezinkomba, ukuphikisana nemiphumela emibi, ziyashintshana.
Kunezifanekiselo ze-Anaprilin hhayi ngokusho kwezinto ezisebenzayo, i.e. lezi yizidakamizwa zeqembu elifanayo lezemithi (beta-blockers) kanye nokubonisa izindawo ezifanayo, kodwa kubandakanya nezinye izingxenye ezisebenzayo. Ngaphezu kwalokho, namuhla kunezidakamizwa eziphephile ezinomsebenzi ofanayo wokukhetha - ukhetha (ukukhetha) beta-blockers. Lezi zidakamizwa, ngokungafani no-Anaprilin ongakhethi, uvimbela umsebenzi wezinhlobo ezithile zezingxenye ze-beta-adrenergic receptor, okudingeka ukuba zenze. Ngakho-ke, akukho mthelela kwezinye izitho, futhi inani lemiphumela emibi yokwelashwa ngezidakamizwa ezinjalo liyanciphisa kakhulu.
Ama-analogs anjalo anamuhla ka-Anaprilin yimithi elandelayo:
- I-Atenolol (i-Atenobene, i-Atenova, i-Ormidol);
- I-Bisoprolol (i-Bidop, i- Concor , i-Cordinorm);
- I-Metoprolol (Vazocardin, Serdol, Corvitol);
- I-Betaxolol (Betac, Lokren, Xonefy);
- Nebivolol (uBinelol, Nebivator, Nebival) nabanye.
Amalungiselelo avela kuhlu olungenhla ahluke ekusebenzeni kwawo, isikhathi sokuthatha isikhathi, isikhathi sokumunca nezinye izinkomba eziningi. Isinqumo salo muthi okufanele sisetshenziselwe ukwelashwa singathathwa yedwa udokotela kuphela, ngokusekelwe kwedatha yezifundo zokuxilonga, izici zomzimba wesiguli kanye nokubekezela kwemithi.
Kunokuba kungenzeka ukuthi ubeke i-Anaprilin esikhundleni se-tachycardia ku-thyrotoxicosis?
I-Thyrotoxicosis yinkinga ye-pathological ebangelwa ama-hormone wegciwane okweqile, lapho zonke izinqubo ze-metabolic emzimbeni ziyashesha. Iziguli ezixilongwa njalo, ngisho nangesikhathi sokulala, ziyakhathazeka ngokukhula kwenhliziyo - i-tachycardia. Isidingo somzimba we-cardiac in oxygen sanda, umzimba usebenza ngokukhululeka. Ngaphezu kwalokho, kuziguli ezine-thyrotoxicosis zingase zenzeke
Ngalesi sifo, i-tachycardia ayinqanyuliwe ngisho nalapho isetshenziswa izidakamizwa eziyisusa kunoma yiziphi ezinye izimo - i-glycosides yenhliziyo (ngaphandle kokuthi isetshenziswe ngaphandle kwezidakamizwa ezinciphisa ukwenziwa kwamahomoni wegciwane). Ngokushesha uthuthukise isimo sesiguli ngalesi simo kungaba i-Anaprilin (kanye nezinye izidakamizwa ezisekelwe ku-propranolol), okunye okunciphisa izinga lamahomoni e-thyroid e-T3. Ngokuqondene nezifanekiselo zika-Anaprilin, ezihlobene ne-beta-blockers ekhethiwe, umphumela wabo ku-tachycardia ngenxa ye-thyrotoxicosis ayisebenzisi kangako. lezi zimali azinciphisi izinga le-T3.