Emzimbeni wesifazane ngamunye, kokubili ama-hormone wesilisa nabesilisa (androgens) akhiqizwa. Ngayinye yalezi zinto eziphilayo zilawula imisebenzi yokuzala, umsebenzi wezinhlelo zangaphakathi. Ukwanda noma ukunciphisa ukuhlushwa kwalezi zinto kuthinta impilo kanye nenhlalakahle jikelele yabesifazane.
Androgens - yiziphi amahomoni abesifazane?
Ama-hormone abesilisa emzimbeni wesifazane akhiqizwa ama-ovari nama-gland adrenal. Zidlala indima ebalulekile ekuhambeni okufaneleko kwezinqubo zamathambo emzimbeni. Phakathi kwemisebenzi esemqoka yalezi zinhlanganisela kukhona:
- ukwakheka kwezitho zobulili;
- ukuthuthukiswa kwesistimu yethambo;
- ukwakheka kwezici zobunikazi zesibili;
- ukuphathwa kokuziphatha ngokocansi.
Ukuhlukunyezwa kwama-hormone emzimbeni wesifazane kuphulwa. Uma i-androgens yabesifazane ingaphezu kwesimiso izikhathi eziningana, odokotela bakhuluma nge-hyperandrogenism, ngokunciphisa inani labo - mayelana ne-hypoandrogenism. Kuhlobo olulodwa lwe-pathology lubonakala ngezibonakaliso zalo siqu kanye nesithombe somtholampilo, ngakho-ke kungenzeka ukuthi lona wesifazane ngokwakhe uphazamise ukuphambene nomkhuba, ngokushintsha okubukeka ekubukeni kwakhe.
Amahomoni abesilisa emzimbeni wesifazane - amagama
Ucwaningo oluqhutshwa izazi ze-physiologists selungile ukuthi emzimbeni wobulili obuhle ngamunye kunezinhlobo eziningana ze-androgens ngesikhathi esisodwa. Kulesi simo, i-hormone eyinhloko ye-hormone ye-hormone e-testosterone yabesifazane besendaweni yegazi iqukethe ukuhlushwa okukhulu kakhulu uma kuqhathaniswa namanye ama-biological compounds aleqembu. Egazini lazo zonke izintombi kukhona:
- i-androsterone;
- androstenedione;
- androstenediol;
- i-dihydrotestosterone.
U-Androgens - okuvamile kubantu besifazane
Ukuze kutholakale ukuhlukunyezwa okwenzekayo kwesimiso se-hormonal, odokotela banquma ukuhlaziywa kwama-hormone wesilisa kubantu besifazane. Ukusola kokuwa okunjalo ngokuguquka okubukeka ekubukeni, ukutholakala kwezici zesifazane. Lapho kuqhutshwa isifundo, inkomba ye-androgen yamahhala isungulwa, echazwa njengephesenti. Ukuchithwa kwalesi sibonakaliso kungabonwa ngezigaba ezahlukene zomjikelezo. I-Androgens kwabesifazane emzimbeni bashintsha ukuhlushwa ezinyathelweni zomjikelezo:
- isigaba se-follicular singu-0.8-9.3%;
- isigaba sokuvuvukala 1,3-17;
- isigaba sokuqondisa ;
- isikhathi sokuya esikhathini sokufika - ku-6.6%.
Ngokuhlukile, ukuhlushwa kwe-testosterone yamahhala kwabesifazane kungasungulwa. Njengoba uneminyaka yobudala, le nkhomba iyashintsha amanani ayo, kodwa akufanele idlule imigomo elandelayo:
- kuze kube yiminyaka engu-9 - 0,06-1,7 picogram / ml;
- 9-13 ubudala - 1.7;
- 13-18 - 4.1.
I-hormone yamadoda ithinta kanjani owesifazane?
Ithonya lama-hormone wesilisa asebenza kowesifazane angahlukaniswa ngokubonakalayo (okusobala ngaphandle kocwaningo) futhi efihliwe. Lapho ama-hormone wesilisa emzimbeni wesifazane equkethwe ngokweqile, lokhu kungenziwa kalula ngokushintsha ukubonakala. Noma kunjalo, umthelela ezingxenyeni zangaphakathi nezinqubo ezenzeka kuzo akucaci. Ngaphansi kwesenzo se-androgens emzimbeni wesifazane kwenzeka:
- ukwandisa izinga lezinyimba ze-glycolytic;
- ukuthuthukisa amaprotheni synthesis;
- kwehla emthamo we-deposit cholesterol;
- ukushisa kwamafutha angaphansi;
- ukwandisa ucansi.
I-androgen engaphezu kwebesifazane
I-predominance yama-hormone wesilisa kubantu besifazane kulula ukukhomba ngokubukeka, umzimba. Iziguli ezinjalo zinamahlombe abanzi, i-man's gait, i-timbre ephansi yezwi. Amandla, amabele, ahlanganiswe izinwele, abanye besifazane baqala ukukhula emasipini nasezintshevu. Ukuguquka kokuhlushwa kwe-androgens kwabesifazane kungaba ngenxa yezici ezimbili:
- Ukwanda kwama-hormone emzimbeni - ukukhiqizwa ngokweqile kwezigulane zabo eziyingozi, ukwehla ezingeni lama-protein ahlanganisa futhi abuye abuyele.
- Izinkinga ezifanelekayo - ama-hormone ahlanganiswa ngokwevolumu evamile, kodwa ama-receptors abonisa ukuzwela ngokweqile kubo.
Ukwedlula ama-hormone wesilisa kubantu besifazane - izimpawu
Izinsolo zokuqala zokwanda kwegciwane legazi le-androgens kumele zivele nezinguquko ekusebenzeni kwezinhlelo zangaphakathi zelungu. Abesifazane abanjalo bayaqaphela:
- ukwephulwa nokuhlukunyezwa komjikelezo wokuya esikhathini , izifo ezivamile zesistimu yokuzala;
- ukwandisa i-insulini egazini;
- ukungabi nesigaba se-ovulatory somjikelezo.
Kodwa-ke, ezimweni eziningi, i-androgens ngokweqile kwabesifazane abanezibonakaliso ezilandelayo zingase zitholwe kakade ekushintsheni kwangaphandle emzimbeni:
- iziphambeko zezithokozi - induna, ukubonakala kwebuso, ukwanda kwezinwele;
- ukwanda okweqile kwesisindo somzimba;
- ukukhiqizwa kwe-sebum okwandisiwe;
- shintsha umbala we-timbre wezwi.
Indlela yokunciphisa ama-hormone abesilisa emzimbeni wesifazane?
Ngaphambi kokunciphisa i-androgens kwabesifazane, odokotela basungula imbangela eyangele ukukhula kwabo. Kulesi simo, isiphetho senziwe ngokuzwakalayo, ngokusekelwe kwiziphetho zongcweti eziningana ngesikhathi esisodwa (isazi sokubeletha, i-endocrinologist, therapist, dermatologist). Inkambo yokwelashwa ikhethwe ngabanye, futhi inqubo ngokwayo kufanele ibe nokugxila okuphelele. Ukuqokwa kwezidakamizwa, isilinganiso sabo, imvamisa kanye nokusetshenziswa kwesikhathi kwenza udokotela. Phakathi kwalawo asetshenziselwa ukunciphisa i-androgens kwabesifazane isetshenziswa:
- I-Metformin;
- Dexamethasone;
- UJanine;
- UDiane-35.
Ukuntuleka kwe-androgens kwabesifazane
Lapho ama-hormone wesilisa abesilisa besifazane engenani elanele, ubulili obuhle kakhulu abukwazi ukubona izinguquko zangaphandle. Ngokungaqondile, lesi sifo siboniswa ukwanda kancane kancane egazini le-cholesterol, elisungulwa ukuhlaziywa kwegazi. Sekuyisikhathi eside, lesi sifo singase singabonakali, ngakho-ke kuvame ukutholakala ekuhloleni okuphelele kwesimo se-hormonal.
Ukuntuleka kwe-androgens kuyathinta impilo yebesifazane nenhlalakahle jikelele. Phakathi kwezifo ezihlobene nokuntuleka kwama-hormone wesilisa:
- i-anemia;
- i-osteoporosis;
- i-atherosclerosis.
I-Androgens kubantu besifazane iyancipha - izimpawu
Uma i-androgens yehla kwabesifazane, izimpawu ezibonakalayo zalesi sifo azikugcini ukulinda. Amantombazane abona ukwehla okubukhali kwesifiso socansi, ucansi olungavamile akulethe injabulo yangaphambili. Ngesikhathi esifanayo, umuzwa wokungabikho kwengqondo, ukucasula njalo. Phakathi kwezinye izimpawu ezibonisa ukuthi i-androgens kwabesifazane iyancishiswa:
- umuzwa ongapheli wokukhathala;
- izinguquko eziningi zemizwelo;
- ukwehluleka kwamathambo.
Indlela yokwandisa izinga lama-hormone wesilisa kubesifazane?
Ukuze kulungiswe ukuhlushwa, ukwanda noma ukunciphisa ama-hormone wesilisa kubesifazane, odokotela baphatha ukwelashwa ngabanye. Kulesi simo, kubalulekile ukucabangela:
- ubukhulu be-disorder;
- isigaba senqubo yokwelapha;
- ukutholakala kwezifo ezithintekayo.
Okokuqala, ngokuzimela ngokwakho kwe-androgen concentration, odokotela batusa iziguli:
- Shintsha indlela yokuphila.
- Qaphela umbuso wosuku (ukuphumula ebusuku hhayi ngaphansi kwamahora angu-8).
- Shintsha ukudla kwakho.
- Yeka imikhuba emibi.
Uma izinyathelo ezithathwe zingezange zenze izinguquko, ukwelashwa kwe-hormone kunqunywe. Isekelwe ekusetshenzisweni kwamalungiselelo e-testosterone. Ukuze uthole ukwelashwa, izidakamizwa ezilandelayo zingasetshenziswa - androgens kwabesifazane:
- I-Omnadren;
- I-Parity;
- Testosterone propionate.