Enye yama-antigen weqembu legazi yi-Rh factor. Ukuba khona kwayo kubonisa ukuthi i-rhesus yakho inhle. Uma kungekho antigen, i-Rh ayibi, futhi lokhu kungaba nomthelela omkhulu ekukhulelweni kwakho esikhathini esizayo. Ngakho-ke, abantu abane-Rhesus enhle bangase bangakhumbuli ngakho, kanti owesifazane onama-blood rhesus angalungile kufanele azi ukuthi ngesikhathi sokukhulelwa, kungaba khona usongo lwe-Rh-impikiswano.
I-Rhesus-impikiswano ibonakala njengomphumela we-ingress of erythrocytes angaphandle egazini lomuntu, elithwala amaprotheni wesistimu yeRhesus. Ukuze amasosha omzimba, angaphandle, futhi ngenxa yalokho, inqubo yokukhiqiza izifo ezilwa namagciwane iqala. Uma ukukhulelwa kuholela kuye, kukhona i-rhesus embi kowesifazane kanye nobaba wengane enhle. Zonke ezinye izinhlanganisela aziholeli ku-Rhesus-impikiswano.
Kodwa-ke, ngisho neRhesus engalungile, ukuhlela ngokugcwele ukukhulelwa kungenzeka kumama. Okokuqala, ukuvimbela okunembile kuvumela ukuthi kungabikho imiphumela ye-Rh-conflict, futhi okwesibili, i-Rh factor negative, ngisho nokukhulelwa kwesibili, akuzona zonke eziholela ekuthuthukiseni kwayo.
Ama-anti-rhesaus amakhemikhali yilawo maqhinga wesakhiwo samaphrotheni akhiqizwa emzimbeni womama lapho kutholakala ama-Rh-positive amangqamuzana egazi obomvu e-fetus. Uma zitholakala egazini legazi, ukuxilongwa kwenziwa-i-Rh-senitization. Lokhu kwembulwa lapho ukuqeda okuzenzekelayo noma okufakelwayo kokukhulelwa kwenzeka nge-rhesus engafanele kowesifazane. Ama-antibodies angabonakala ngesikhathi sokukhulelwa kokuqala, lapho igazi lomntwana one-rhesus elihle lingena egazini labesifazane abane-rhesus embi ngemva kokuzalwa.
Kwezinye izimo, ukukhushulwa kunokwenzeka ezinkathini zokuqala, ngoba izifo zomzimba zivela egazini legazi, kusukela ngeviki lesi-7 lokukhulelwa. Nakuba ngokuvamile ukukhulelwa kokuqala kwabesifazane abane-Rh factor engalungile kungenzeka ngaphandle kokucindezeleka, uma ngaphambilini kwakungekho ukugqugquzelwa komzimba.
Ukwakhiwa kwe-Rhesus kungathuthuka, uma kwenzeka kususwa ngokuzenzakalelayo kwe-placenta, futhi uma ukuzalwa kokuqala kuhambisana nokuphuma kwegazi noma owesifazane obelethayo yi-cearean. Futhi-ke, lokhu kwenzeka uma kwenzeka okwesibini (okwesithathu) ukukhulelwa nge-rhesus engalungile kumama. Lokhu kungenxa yamathuba aphezulu ukuthi amangqamuzana amaningi egazi abomvu ase-Rhesus angangena egazini legazi lomama. Futhi-ke, ama-anti-Rhesus antibodies azoqala ukwakha.
Ngenxa yokuthi isimiso somzimba samasosha omzimba esinama- rhesus amabi ngesikhathi sokukhulelwa senziwa ngamaseli abomvu e-fetus (i-Rh-positive) okokuqala, amasosha omzimba akhiqizwa kakhulu. Futhi ku-10% yabesifazane emva kokukhulelwa kokuqala kunomgogodla. Ngakho-ke, uma owesifazane onama-Rhesus angenakugwema ukugoma kukaRhesus, bese ekukhulelweni kwesibili amathuba okubukeka kwakhe azophinde abe ngu-10%. Ngakho-ke, kubalulekile nge-rhesus embi kowesifazane ngaphambi kokuqala kokukhulelwa kwesibili ukudlulisa ukuhlaziywa ukuze kutholakale ukuthi kukhona ama-antibodies egazini. Ngalesi sikhathi, kufanele abhaliswe kakade nesikhungo sezokwelapha. Esikhathini esilandelayo lapho, futhi ungaqhuba ukuhlolwa okwengeziwe.
Futhi, nge-rhesus engakahle ngaphambi kokuhlela ukukhulelwa okwesibili, kubalulekile ukuthola ukuthi i-Rh factor ingumntwana wakho wokuqala.
Le nkinga, njengokukhulelwa okuqhubekayo kwabesifazane abane-rhesus engafanele, kaningi kwenzeka ngesikhathi sokuqala kokukhulelwa (kuze kube amasonto angu-14). Ukufa komntwana ongakazalwa emva kwamasonto angu-28 kunokwenzeka.
Phakathi kwezinyathelo ezithathwe ngesikhathi ukhulelwe owesifazane onesifo esibi, kungenzeka ukuba afake, ngaphezu kwenqubo eyenza ukuhlanzwa kwe-antibodies, kanye nokumpompela igazi kwe-intrauterine kwengane.