I-HPV (igciwane lesandulela ngculaza) isifo sokutheleleka ngegciwane lesandulela ngculazi sithathwa njengenye yezinto ezivame kakhulu. Kunezinhlobo ezingaba ngu-100 zegciwane. Ezinye zazo azilimazi, kanti ezinye zibangelwa umdlavuza. Umgomo wokugada i-Gardasil uzokusiza ukuvikela umzimba futhi ukwenze umelane nomsebenzi wegciwane.
I-Gardasil - ukwakheka
Ukuze imithi ikwazi ukulwa nokutheleleka ngokuphumelelayo, ingxenye yayo kufanele ibe negciwane ngokwayo. Ukwakhiwa kwalo mgomo kuhlanganisa ingxube yezinhlayiyana ezifana ne-virus-like pure-like-6, 11, 16 no-8 izinhlobo zamaprotheni L1. Ngaphezu kokuziphatha kwezingxenye, i-Gardasil iqukethe izinto ezinjalo ezisizayo njenge:
- i-hydrophosphate aluminium sulphate amorphous;
- i-chloride ye-sodium;
- i-polysorbate - 80;
- L-histidine;
- i-sodium borate.
Umuthi wokugoma awuqukethe izidakamizwa noma izinto zokulwa ne-antibacterial. Ngaphandle, ukulungiswa ukumiswa okumhlophe. Umuthi wokugaya iJasasil uthengiswa ngama-flacon kanye namasringe alahlayo ngenaliti. Umthamo ojwayelekile u-0.5 ml. Gcina lesi sidakamizwa endaweni evikelekile ekukhanyeni kwelanga ekushiseni kwama-2 kuya kwangu-8 degrees. Ezimweni ezinjalo, ingakwazi ukugcina izidakamizwa iminyaka emithathu.
Gardasil - ubufakazi
Ukulungiselela kuthola ama-microparticles ezithathelwanayo. Ziningi kangaka ukuthi azikwazi ukulimaza. Umsebenzi oyinhloko we-VHF ukuwusebenzisa ukuzivikela komuntu siqu futhi uqale ukwakheka kwama-antibodies antiviral. Lokhu kunikeza ukuvikeleka okunamandla okuhlala isikhathi eside. Futhi ngisho nakulezo zinhlobo zokutheleleka, ama-antigens okungafakwa kulowo mgomo.
I-Gardasil umgomo wokulwa ne-papillomavirus yabantu futhi isetshenziselwa ukuvimbela. Ukugonywa kuvunyelwe kusuka eminyakeni engu-9 ukuya kwezingu-45. Isidakamizwa sisiza ukuvimbela i-neoplasia ye-intraepithelial, i-adenocarcinoma, umdlavuza womlomo wesibeletho , isisu, i-vulva, i-anus, futhi ivimbela izinhlamvu zangasese ukuba zingabonakali ezithombeni zangaphandle.
I-Gardasil - uhlelo lokusebenza
Umuthi kufanele ugonywe nge-intramuscularly esifundeni esiphezulu esiphakathi kwesithathu kwethanga noma imisipha ye-deltoid. Ukuze ukuphathwa ngendlela engalungile umuthi awubalwa. Kungakhathaliseki ubudala, umthamo owodwa u-0.5 ml wezinto. Kunconywa ukuthi unyakaze ukumiswa ngaphambi kokusetshenziswa. Ngemuva kokujola, odokotela kufanele balandele isimo sesiguli kungakapheli isigamu sehora.
Isikhathi sokugoma saseGarasil sinezilinganiso ezi-3. Okokuqala kufakwe ngosuku olucacisiwe. Owesibili - izinyanga ezimbili emva kokuqala. Futhi kwezinyanga ezintathu - ezinyangeni ezingu-6 emva kokuqala. Elinye icebo liyakwazi futhi - liphuthumayo, ngokusho ukuthi yimuphi umgomo wokugoma waseJardasil unikezwa ngenyanga, kanti nezinyanga ezintathu-ezintathu emva kwalo. Uma isikhala phakathi kwemigomo siphulwa, kodwa sonke senziwa phakathi nonyaka owodwa, inkambo ibhekwa njengephelele.
I-Gardasil - imiphumela emibi
Njenganoma iyiphi enye inqubo, ukugoma neGarasil kungabangela ukusabela okungafuneki emzimbeni. Kodwa azivamile - cishe amacala angu-1%. Phakathi kwemiphumela emibi eyinhloko ebangelwa ukugoma i-Gardasil, singakwazi ukuhlukanisa okulandelayo:
- ukucheka kwendawo;
- ubuhlungu esakhiweni somjovo;
- umkhuhlane;
- ikhanda;
- i-gastroenteritis;
- i-asthenia;
- izinqubo zokuvuvukala ezithombeni zomzimba;
- i-thromboembolism;
- i-anaphylaxis;
- i-myalgia;
- ubuhlungu obuhlangene;
- i-urticaria;
- ukuphelelwa amandla;
- ukuvuvukala kwendawo;
- i-pyrexia.
Imiphumela ye-Gardasil
Ukugonywa kwasungulwa yi-immunologist uJan Fraser wase-Australia. Ngo-2006, yamukelwa yizithunywa ze-US Food and Drug Administration. Ngokushesha yaqala ukuthumela emhlabeni jikelele. Kungakapheli isikhathi kwamanye amazwe umgomo olwa ne-HPV Gardasil wawuvinjelwe. Wayebhekwa njengengozi engozini, ekwazi ukulimaza impilo.
Ingozi eyinhloko ukuthi i-Gardasil ukungabi namandla kungabangela. Akukho miphumela yocwaningo olusemthethweni. Kodwa odokotela kwakudingeka babhekane nezimo eziningana, lapho emva kokugoma noma kunjalo i-oncology yakhula, futhi lapho kubangelwa ukuhluleka komjikelezo. Ngaphezu kwalokho, abanye ochwepheshe bayaqiniseka ukuthi ukuhlolwa kwesidakamizwa kwenziwa ngokuphulwa okukhulu.
I-Gardasil - ezifanayo
Ukubuyekezwa okungalungile kukuphoqa ukuba ubheke amanye ama-compounds angakwazi ukuvikela ngokumelene ne-papillomavirus yabantu futhi okwamanje akenzi umonakalo. Umgomo wokulwa ne-HPV ugcwaliswe ngokuphelele. I-Gardasil ingaba ukulungiswa kwe-Cervarix. Uma ufuna i-analogue yokumiswa kwezakhiwo zokwelapha, ungakhetha emithini elandelayo:
- Viferon;
- I-Ferrovir;
- I-Allokin-alpha;
- Galavit;
- I-Isoprinosine;
- I-Panavir;
- Ubulili be-Epigen.
Cervarix noma Gardasil - okungcono?
Zombili imishanguzo yenzelwe ukuvikela nge-HPV futhi ingenayo amagciwane wangempela - aphile noma abulawe. Izinto eziyinhloko kuzo zidalwe ngamagobolondo angenalutho ahambisana nezimvilophu zala ma microorganisms. Kokubili i-Gardasil ne-Cervarix kufanele igwetshwe. Imiphumela emibi emva kokugoma ayilula. Futhi uma kwenzeka, khona-ke babonakala ikakhulukazi ngokuhlunguphaza noma ubuhlungu obufushane endaweni yomjovo.
Empeleni, lezi zidakamizwa ezimbili zifana ncamashi. Ukwahlukana okuwaziwa kuphela okwamanje - I-Cervarix ikhuthaza ukwakhiwa kokumelana nezinhlobo ezingu-16, 18, 33 no-45 ze-HPV. Futhi umgomo olwa negciwane leGarasas uneminyaka engu-16 no-18 kuphela. Ngaphezu kwalokho, i-Cervarix inezibuyekezo ezimbalwa ezingalungile, ngakho-ke ungamnika okuthandayo kusuka kokumiswa okwesikhashana okuthunyelwe. Noma kunjalo, igama lokugcina kufanele libe ngumpetha.
Iqiniso NgeGadasil
Nakuba umkhiqizi wezidakamizwa futhi ethi ukumiswa akuyona into engenabungozi, imibhikisho iqhutshwa kuwo wonke umhlaba. Izishoshovu zithi ukugonywa kweGarasil kuyingozi empilweni futhi kungaqondakali kahle. Futhi uma uqonda, lezi zitatimende azikude neqiniso. Abamukeli bayakwazi kancane ngemiphumela yokucwaninga ngezidakamizwa. Futhi izisulu nemindeni yabo zikhuluma ngokukhululekile ngamacala okulimaza empilweni yabo.
Akunakwenzeka ukuloba ukuthi i-Gardasil iyimbangela yokunqamuka kokuya esikhathini ngaphambi kwesikhathi, i-oncology noma ukufa. Izisulu ziyazi ngokuqinisekile ukuthi izinguquko zaqala ukwenzeka ngemuva kokugoma. Futhi bakhuthaza umhlaba ukuthi ungazitholi impilo futhi ngaphambi kokunquma ukugoma ngokuningiliziwe ukuze ufunde okuyinhloko yenkambiso futhi ucabange izikhathi eziyikhulu.