Umsebenzi oyinhloko wamasosha omzimba ukubunjwa okulungile kokuphendula okuvikelayo kwenyama ekuphenduleni ukungena kwamagciwane. Ngakho-ke, kubalulekile ukulalela imiphumela yokuhlolwa kwegazi futhi uthathe izinyathelo ezifanele uma i-lymphocytes iyancipha ngisho noma inani layo liyanqatshwa emiphakathini evamile, ukuqapha ukuhlushwa.
Izimbangela zokubala okuphansi kwe-lymphocyte egazini
Amazinga avunyelwe amangqamuzana omzimba omzimba abhekene nawo angama-18 kuya kuma-40%. Izinguquko kulezi zigaba zingenzeka ngokucindezeleka, ngokweqile, kubesifazane, ukushintshashintsha kwesinye isikhathi kubangelwa ukuqala komjikelezo wokuya esikhathini.
Izinga eliphansi le-lymphocyte egazini libonisa ukuthuthukiswa kwe-lymphopenia. Lesi simo sibonakala ngokufuduka kwamangqamuzana ahlonywe kusuka emithonjeni yezinto eziphilayo ezijikelezayo ezitsheni ezithinta izicubu lapho kuqala khona ukuvuvukala. Izifo ezilandelayo zingabangela:
- i-septic, i-pathologies ye-purulent;
- isifo sofuba sezimayini;
- I-AIDS;
- izilonda ezinamandla ezithathelwanayo;
- i-lupus erythematosus (isakazwa);
- lymphogranulomatosis;
- i-splenomegaly;
- i-Itenko-Cushing syndrome;
- i-lymphosarcoma;
- imisebe kanye ne-chemotherapy;
- izilonda ze-hepatological ezingapheli;
- i-chlorosis;
- i-aplastic insemia ;
- isiteji esincane sokulwa nokushaqeka;
- ukubhujiswa kwama-lymphocytes;
- i-immune pathologies yokuzalwa;
- ukuhluleka kwezinso;
- ukudakwa nge-corticosteroids.
Kumele kuqashelwe ukuthi lezi zici ziyisici se-lymphopenia ngokuphelele. Lokhu kusho ukungafiki okuphelele kwanoma yiluphi uhlobo lwe-lymphocytes egazini.
Ifomu lesihlobo salesi simo sibonisa ukuthi iphesenti ye-lymphocytes kwezinye izinhlobo ze-cell ku-formula ye-leukocyte iphazamiseka. Njengomthetho, i-lymphopenia enjalo isuswa kalula futhi isheshe, ngoba akusiyo njalo uphawu lwezinqubo ezinkulu zokuvuvukala.
Kulaba besifazane abakhulelwe, inani le-lymphocyte libuye linciphise. Lokhu kungenxa yemvelo yemvelo evumela ukuthi i-ovum ikhule. Uma kungenjalo (ngenkathi kugcinwa izinga elivamile lamaseli omzimba omzimba), i-lymphocytes izobona izakhi zofuzo zesilisa njengezinye izizwe futhi, ngokufanele, zenze iqhaza ekwakheni impendulo enonya, zivimbele ukungena kwazo, ngaleyo ndlela zingabandakanyi amathuba okukhulelwa.
Ama-lymphocytes anciphisa futhi ama-monocytes aphakanyisiwe ekuhlolweni kwegazi
Ukusabela kwamasosha omzimba kuhlanganisa ukumuncwa kwamangqamuzana angaphandle kwamapathogenic, bese ekuqedeni kwabo. Kule nqubo, i-monocytes ne-lymphocytes iqhaza, ngakho-ke amaphesenti abo egazini abalulekile, ekhombisa ukuthi kukhona noma ukungabi khona kwesibindi. Ukwehlukana kwamakilasi avela kumazinga ajwayelekile kubonisa isifo esithathelwanayo noma sesandulela ngculaza.
Ukwanda kwamakhamera amaningi, lapho i-lymphocytes egazini iyancipha, kubangela izizathu ezilandelayo:
- isifo sofuba;
- isigaba sokuqala se-mononucleosis;
- izilonda ze-fungal;
- i-syphilis;
- lymphogranulomatosis;
- i-ulcerative colitis;
- i-leyemia ye-myeloid yefomu elingapheli;
- i-sarcoidosis;
- i-leukemia esiteji esinzima;
- isikhathi sokuqala sokubuyiselwa komzimba ngemuva kokusebenza.
Kumele kuqashelwe ukuthi izici ezibangela ushintsho olunjalo emangqamuzaneni omzimba angase zibe izifo ezilula, isibonelo, umkhuhlane, izifo ezithinta ukuphefumula noma izifo ezithinta ukuphefumula.
I-mononucleosis ayidabuli ngokuhambisana nokunciphisa ngesikhathi esisodwa kwinani lama-lymphocytes, lokhu kufana kuphela nezigaba zokuqala zesifo. Ekuthuthukiseni phambili intuthuko yayo, ukuhlunga kwamangqamuzana kukhula ngokweqile nama-monocytes, futhi ngesikhathi esifushane kakhulu.