I-gonadotropin ye-chorionic yabantu i-hormone evela eqenjini lama-glycoprotein, okubonisa ukuqala kokukhulelwa emzimbeni wesifazane. Kubukeka kumchamo we-chorionic gonadotropin ekukhulelwe futhi kuchaza ukubukeka kwamapheshana amabili esivivinyweni. Ukulandela ukuguqulwa kokukhula kwe-gonadotropin ye-chorionic ngesikhathi sokukhulelwa, kungenzeka ukwazi ukwahlulela ukuthi ukukhulelwa kuqhubeka kanjani.
I-gonadotropin ye-chorionic ekukhulelweni ivamile
Ngokuvamile, emadodeni nakwabesifazane abakhulelwe, izintambo ze-β-hCG ezivela ku-0-5 mU / ml. Izinga le-gonadotropin ye-chorionic liqala ukwanda kakade ezinsukwini zokuqala emva kokufakelwa kombungu emgodini we-uterine. Ikhiqizwa yizicubu ze- chorion futhi idlala indima ebalulekile esimweni esijwayelekile sokukhulelwa. Ngakho-ke, i-gonadotropin ye-chorionic yabantu ikhuthaza ukwakheka kwe-placenta, iphinde isekele ukusebenza okuvamile komzimba ophuzi (ukukhiqizwa kwe- hormone progesterone ). Ngemuva kokufakwa kwe-placenta, kuthatha umsebenzi wokwenza i-gonadotropin ye-chorionic.
Ekuqaleni kokukhulelwa, njalo ezinsukwini ezimbili kuya kwezintathu, isibonakaliso se-h-hchch (i-chorionic gonadotropin yabantu) siphindwe kabili. Kusukela ngeviki le-10-11 lokukhulelwa, amazinga okukhula ku-hCG ahamba kancane, njengoba i-placenta iqala ukuqala futhi iqala ukuthatha umsebenzi wokukhiqiza ama-hormone wokukhulelwa. Ngakho, emavikini okuqala okukhulelwa, izinga le-gonadotropin ye-chorionic egazini liphakathi kuka-25-156 mU / ml. Izinga le-gonadotropin lama-chorionic 1000 mU / ml lihambisana neviki lesithathu lokukhulelwa. Emasontweni angu-4-5 lesi sibalo singu-2560-82300 mU / ml, emavikini angu-7-11 emva kokukhulelwa izinga le-gonadotropin ye-chorionic egazini lifinyelela ku-20900-291000 mU / ml, futhi emavikini angu-11-12 kakade wehla ku-6140-103000 mU / ml.
I-gonadotropin yama-Chorionic inamaconsi amabili - i-alpha ne-beta. I-subunit ye-alpha ifana ngokuhlelekile neyama-hormone evuselela, e-luteinizing ne-follicle-stimulating. I-subunit ye-beta iyingqayizivele ngesakhiwo sayo.
I-Gonadotropin ye-chorionic - sebenzisa
I-gonadotropin ye-chorionic yomuntu isetshenziselwa ukwelapha ukungasebenzi (ukushukunyiswa kwe-ovulation nge-in vitro fertilization, ukugcinwa komsebenzi womzimba ophuzi). I-gonadotropin yama-Chorionic yamadoda inqunyelwe ukukhuthaza i-spermatogenesis nokukhiqizwa kwe-androgens (ngezinye izikhathi esetshenziswa ezemidlalo njenge-doping).
Ukusetshenziswa kwe-gonadotropin ye-chorionic kuboniswa kulezi zifo ezilandelayo:
- kubesifazane abanesisindo esanele (i-stimulation of the ovulation and maintaining the body of the yellow body);
- emadodeni anokuthuthukiswa kwamathambo, aphuze ubusuku, ubuzenzisi be-hypogonadotropic hypogonadism.
Isidakamizwa se-gonadotropin chorionic sinqatshelwe lapho:
- izicubu zezinhlayiya zocansi, kanye nezinye ezibangelwa ukungasebenzi kahle kwegonads;
- cryptorchidism ebangelwa i-female hernia, ukulimala nokuhlinzwa;
- ukubekezelelana ngabanye kwe-gonadotropin ye-chorionic.
Indlela yokuphoqa i-gonadotropin ye-chorionic?
- Isixazululo se-chorionic gonadotropin sitholakala njengomjovo. Izijovo ze-intramuscular ye-gonadotropin ziyahlakazeka kahle futhi zenziwa ngokwemigomo kadokotela.
- Eminye imiphumela emibi ingabonakala ikhuphukile i-viscosity yegazi kanye nezinkinga ezihambisana ne-thromboembolic, kanye nesifo se-ovarian hyperstimulation. Abafana bangakhulisa okwesikhashana izigulane zabo ezincane, bangase bahlakulele ukuvuvukala kanye namagciwane.
Sihlolisise indima ye-gonadotropin ye-chorionic emzimbeni wesifazane okhulelwe, futhi sazi kahle ukusetshenziselwa kokufana kwayo.