Isiphakamiso ngokuthatha ithempulethi ye-Mezim ngaphambi komkhosi siyaziwa wonke umuntu. Kodwa kuthiwani uma kungekho mithi ekhemisi? Futhi ingabe lesi sidakamizwa singashintshwa ngamaphilisi eshibhile? Namuhla sizocabangela ukuthi yiziphi izimo ezifanayo zeMezim, futhi yikuphi umehluko wabo oyinhloko.
Yikuphi okungcono - i-Pancreatin noma i-Mezim?
I-Pancreatin yinto e-enzyme ekhishwa kuma-pancreas ezinkomo. Iqukethe ama-enzyme amathathu e-pancreatic:
- i-amylase (ikhuthaza ukuwohloka kwama-carbohydrates);
- i-protease (isika amaprotheni);
- lipase (ihlanza amafutha).
Ukudayiswa kwePancreatin ngendlela yamathebulethi ngegama elifanele, noma njengengxenye yeminye imithi:
- I-biofestal;
- I-Normoenzyme;
- Okujabulisayo;
- Enzistal;
- I-Festal;
- I-Pancreoflate;
- Biosim;
- Pancreatym;
- Enzibene;
- I-Panzinorm;
- I-Gastenorm;
- I-Creon;
- Mikrazim;
- Penzital;
- I-Pancrelipase;
- I-Pancrenorm;
- I-Pantcitrate;
- I-Vestal;
- Uni-Festal;
- I-Panzim;
- Hermitage.
Kodwa i-analogue ethandwa kakhulu ye-Pancreatin yi-Mezim, engashintshwa yizidakamizwa ezibalwe ngenhla, ngoba zonke zazo njengezinto ezisebenzayo eziqukethe ama-enzyme e-pancreatic.
Uyini umehluko phakathi kwezidakamizwa?
Imithi efakwe ohlwini iqukethe umthamo ohlukile we-amylase (ngokuvamile isibalo esilandelayo negama le-enzyme). Ngakho-ke, isibonelo, i-Mezim Forte 10000 (i-analogue - Creon 10000, i-Mikrazim 10000, i-Pazinormm 10000) inezinhlamvu ezingu-10,000 zama-amylase. Isilinganiso esinamandla kunama-25,000 ED (Creon, Mikrazim), kanti obuthakathaka yi-3500 ED (Mezim-Forte). Kulezi zilungiselelo njenge-Festal, Digestal, Penzital, Enzistal iqukethe u-6000 ED we-enzyme.
Ngaphandle kokuhlushwa kwe-amylase, ukufaniswa kukaMezim Forte kuhlukile kokuqukethwe kwezinto ezengeziwe. Ngakho, isibonelo, ku-Festal, Digestal ne-Enzistal kune-hemicellulase ne-bile. Imithi emithathu efanayo yiziphilisi zamasayizi ajwayelekile, kanti i-Pazinorm, i-Creon, iHermitage neMikrazim yi-capelules ye-gelatin, ngaphakathi kwayo yi-microtabules ene-diameter engaphansi kuka-2 mm (ngenxa yalokhu isenza ngokushesha).
Izinkomba zokusetshenziswa
Ukwelashwa kwe-enzyme kuboniswa i- cystic fibrosis ne-pancreatitis engapheliyo, uma kunokuntuleka kwe-exocrine kwe-pancreas. Ukusetshenziswa kwe-Mezima (noma isifaniselo sayo eshibhile se-pancreatin) kufanelekile ngenxa yokuphazamiseka kokugaya ukudla okubangelwa izifo ezingapheli zesifo esiswini, isibindi, isisindo somzimba, esiswini, futhi ngemuva kwe-irradiation noma ukuthengiswa kwalezi zitho.
Njengoba imfundo yokusebenzisa le mithi ibonisa, i-Mezim ithuthukisa ukusebenza komgudu wokugaya ukudla kubantu abaphilile uma kwenzeka bedla ngokudla. Futhi, umuthi unqunywe ngaphambi kwe-ultrasound yezinhlelo zokugaya ukudla noma i-X-ray.
Ungathatha kanjani i-Mezim kanye nezifaniso?
Ama-enzyme okugaya aqala ukwenza okuthile, awela emathunjini amancane: kusukela esenzweni esonakalisa ijusi esiswini avinjelwe igobolondo elikhethekile lethebhulethi, eliphela kuphela pH = 5.5.
Amathebulethi athathwa ngesikhathi sokudla, ahlanjwe ngamanzi noma amajusi wezithelo (kodwa hhayi ngeziphuzo ze-alkaline).
Umsebenzi ophakeme we-enzyme ye-pancreatic uyaphawulwa ngemva kwemizuzu engama-30 kuya kwengu-40 emva kokuthatha i-Mezima Forte noma i-analogues yayo.
Ukuqapha
Naphezu kokuthi zonke izinhlobo ezibalulwe ngenhla zeMezim Forte - zombili ezishibhile futhi ezibizayo - ziqukethe i-pancreatin (i-amylase, i-lipase, i-protease), nakuba yizingxube ezihlukene, kuyingozi ukubeka lezi zidakamizwa zodwa.
Isibonelo, ngezihlalo eziningi, i-Festal ayinconywa, futhi ngokujwayelekile amalungiselelo enzyme aqukethe i-bile aphikisana neziguli ezinezinambuzane ezingasebenzi kahle noma umsebenzi we-gallbladder.
Umthamo wansuku zonke we-amylase unqunywa udokotela, njengoba uhlaziye isimo sesiguli. Kumuntu, yizinyunithi ezingu-8 000 - 40,000, futhi uma ama-pancreas engenzi izinyimba nhlobo, umzimba udinga ama-amylase angu-400,000.
I-Mezim ne-analog yayo engavamile kakhulu ibangela imiphumela emibi - iboniswa ikakhulukazi ngokuvimbela emathunjini.