I-AST yisifushaniso se-aspartate aminotransferase, i-enzyme yangaphakathi ye-intracellular edlala indima ebalulekile ekusetshenzisweni kwe-amino acids. I-enzyme ibonisa umsebenzi omkhulu kunazo zonke ezinkambisweni zokuxilonga, okwenzeka ezinhlakeni zesibindi, izinso, inhliziyo, imisipha yamathambo nezinye iziphetho zezinzwa.
Ukuhlolwa kwegazi ku-AST kuyinto evamile kubantu besifazane
Isilinganiso esimaphakathi se-AST egazini labesifazane kubhekwa njengezinga lama-20 kuya kwangu-40 amayunithi ngetitha. Kulesi simo, izinkomba eziphansi zingenzeka, futhi inqubo yenkinga enkulu ye-pathological yi-AST index engaphansi kwama-5 amayunithi ngetitha. Izinkomba ezikhulayo zibhekwa njengezifanelekile ukunakekelwa uma umzingcele udlula ama-45 amayunithi ngetitha.
Futhi, ekuhlaziyweni kwezinga le-AST kubesifazane, kufanele kubone ukuthi isilinganiso sakhe sincike eminyakeni yobudala. Ngakho-ke, kuze kube yiminyaka engu-14, inkomba ibhekwa njengamayunithi angu-45, ngokunciphisa kancane kancane. Futhi kuphela uma uneminyaka engama-30 umkhawulo ongaphezulu wokujwayelekile uhlelwe ngamayunithi angu-35-40 ngetitha ngalinye.
Ngaphezu kwalokho, kufanele kuqashelwe ukuthi emithi, izindlela eziningana ezisetshenziselwa ukunquma le nkomba, futhi izindinganiso ezijwayelekile ziyahlukahluka kuye ngokuthi iyiphi esetshenziswayo. Ngakho-ke, incazelo yokuhlaziywa kufanele yenziwe ngumchwepheshe.
Izinga eliphezulu le-AST egazini
Amacala uma izinga le-AST egazini liphansi kunejwayelekile, kokubili kwabesifazane nakwabesilisa, akuvamile kakhulu, futhi bakholelwa ukuthi inkomba enjalo ayinalutho olubalulekile lokuxilonga. Lokhu kubangelwa ukuthi umkhawulo ophansi we-indicator evamile kunengqondo, futhi ngisho ne-indicator yama-10-15 amayunithi angeke kubhekwe njengenkomba enembile yokutholakala kwe-pathologies.
Ukuncipha kwezinga le-AST kungase kube ngenxa yokuthi:
- ukukhathala okujwayelekile;
- ukungabi nevithamini B6 ;
- isiteji sokugcina se-cirrhosis noma omunye umonakalo omkhulu wesibindi (ukwehla okubukhali emanzini, ngaphansi kwamayunithi angu-5 ngelitha ngalinye).
Izinga elikhuphukile le-AST egazini
Ngokuvamile, izinkomba ezengeziwe ze-AST zivame kakhulu futhi zingabonisa:
- i-cirrhosis, i-hepatitis enzima (ngokuvamile ukuphuma kwe-ACT kuyaphawuleka futhi kungadlulela okujwayelekile ngezikhathi ezingaphezu kuka-20);
- i-dystrophy yama-muscular ne-dermatomyositis (engaphezu kwesimiso ngezikhathi ezingu-8);
- i-pancreatitis ejulile , izifo zegazi, izigaba zokuqala zesibhedlele (2-5-ngokuphindwe ngokweqile);
- i-thromboembolism yomthambo we-pulmonary (okungaphezu kokujwayelekile ngezikhathi ezingu-2-3).
Ngaphezu kwezinkinga ezingenhla, ukwanda kwezinga le-AST kubonakala ekuhlaselweni kwe-angina nokuhluleka kwenhliziyo.