Kuze kube manje, i-gentamicin ekujozeni ibhekwa njengama-antibiotic aqinile wezenzo eziningi. Ukungena ngaphakathi kwamangqamuzana amabhaktheriya nge-membrane, i-gentamicin idabukisa ngokuqondile ukuqala kweprotheyini ye-pathogen. Isebenza kakhulu ngokumelene ne-Pseudomonas aeruginosa, ama-bacteria agciwane kanye ne-Gram-positive cocci, kuhlanganise nalabo abaphikisana nezinye izinhlobo zama-antibiotic.
Ukukhululwa kwefomu nokubunjwa kwe-Gentamycin
Isidakamizwa sitholakala ngendlela yamafutha, amaconsi eso, i-powder yokulungiselela isisombululo somjovo, i-liquid for injections (gentamycin sulfate). Ukwakhiwa kwalokhu okugcina, ngaphezu kwezinto eziyinhloko, kuhlanganisa:
- metabisulfite sodium;
- i-hydrodium i-sodium;
- i-sulfuric acid;
- usawoti we-disodium.
Izinkomba zokusetshenziswa kwe-Gentamycin
Isidakamizwa Gentamicin, ngokuvamile esetshenziselwa izifo ezinzima. Isebenza kahle ekwelapheni iziguli ezine-immunity, okuyisici seziguli ezine-diabetes, i-leukemia, njll.
I-Gentamicin yama-Parenteral isetshenziselwa ukwelashwa:
- izifo ezithathelwanayo zamathambo namathambo, isikhumba (kubandakanya ukushisa okujulile kanye nesithwathwa );
- izifo zokuphefumula eziyinkimbinkimbi kanye nezitho ze-ENT;
- ukuvuvukala okukhulu emgodini we-urinary nesigxobo esiswini;
- ukutheleleka kwesistimu yenzwa yomphakathi.
Amagciwane e-Gnatamycin ngokuvamile asetshenziselwa ubuchopho. Ngezinqubo zokuvuvukala kulezi zingxenyekazi kwabesifazane, lesi sidakamizwa silawulwa ngaphakathi. Ngenxa yokusetshenziswa kwemithi elwa namagciwane, kungenzeka ukuvimbela izinkinga ezinzima zomzimba, kubandakanya ukungabi nabantwana .
Imiyalo yokusetshenziswa kwe-Gentamicin kuma-ampoules
Isidakamizwa se-Gentamicin singasetshenziselwa umzimba wesiguli kokubili ngaphakathi nangenhliziyo. Ukusetshenziswa okugulisayo, umthamo owodwa wesidakamizwa uhlanjululwe nge-50-100 ml yesisombonic i-chloride isixazululo noma inani elifanayo lesisombululo se-5% se-glucose. Iziqondiso zithi isilinganiso se-Gentamicin nsuku zonke kumjovo omdala singama-3 kuya ku-5 mg ngesisindo segciwane lesisindo somzimba, izingane ezingaphezu kweminyaka engu-14 ubudala ziyi-0.8 kuya ku-1.2 mg ngesisindo somzimba, kanti le mali ihlukaniswe ngama-2 kuya ku-4. . Inkambo yokwelashwa yimizuzu engu-7 kuya kwezingu-10. Udokotela ozoya khona angenza izinguquko ngokusekelwe ebucayi besifo, iminyaka yesiguli, njalonjalo. Uphinde anqume ubude benkambo yokwelashwa, okuyinto, ikakhulukazi ebucayi, engasetshenziswa isikhathi eside.
Ukungafani nemiphumela emibi yejojo ​​Gentamycin
Ukusetshenziswa kwe-Gentamicin akuvumelekile:
- ngokuzwela okwedlulele kwesiguli kuma-antibiotics weqembu le-aminoglycoside;
- ukuphulwa kwezinso zokusebenza;
- i-neuritis ye-nerve auditory;
- ngesikhathi sokukhulelwa kanye ne-lactation.
Lapho ukwelashwa kweGentamicin, izenzakalo ezimbi ezilandelayo zingenzeka:
- isicanucanu, ukuhlanza;
- ikhanda;
- ubuthakathaka bemisipha;
- ukuxubha;
- isikhumba ukusabela okweqile;
- ukuphazamiseka kwamabhuku;
- ukulahlekelwa umuzwa wokulinganisela.
Isidakamizwa sinakho ukuqhuma, ngakho-ke, ngokuphazamiseka kwezinso ezisebenzayo, izilonda zezinyosi zivame ukuphawula.
Kwezinye izimo i-Gentamicin iyingozi kakhulu emzimbeni wesiguli. Umthelela omubi wezidakamizwa eziphethwe yizinzwa ezihlobene nokusebenza kwezixhobo zokuzwa ne-vestibular kwaphawulwa. Kulesi sixhumano, isiguli kufanele sibe ngaphansi kokulawulwa udokotela, ikakhulukazi lapho umthamo omkhulu wezidakamizwa ushiwo noma inkambo yokwelashwa iqhubeka. I-Gentamicin ayinqunywe ngokuhlanganiswa nemithi elwa namagciwane ephethe umphumela we-nephro- noma ototoxic. Futhi nakuba kungenayo idatha eqondile ekusebenzisaneni kwe-gentamicin kanye nokujova utshwala, izazi zeluleka kakhulu ukuba zigweme ukuphuza ngesikhathi sonke sokwelashwa.