Ukulungiswa kwe-Polyoxidonium ingenye ye-immunomodulators ephumelelayo esiza izitho zomzimba kanye nomzimba wonke ukulwa nezifo ezihlukahlukene. Kuvame ukushiwo njengengxenye yezokwelapha eziyinkimbinkimbi zezifo ezinzima, ngezinhloso ze-prophylactic, zokubuyiselwa kwegciwane ngemuva kokudlulelwa kwamathambo.
Isidakamizwa esibuzwayo sinezinhlobo eziningana zokukhululwa: amaphilisi (okusetshenziselwa ukukhuluma ngomlomo nangokwesekela), i-lyophilizate yokulungiselela isisombululo (for intranasal and parenteral usage) suppositories (ukuphathwa kwamasipha kanye nama-rectal). Sizokwazi kabanzi ngemininingwane ye-Polyoxidonium ukulungiselela ukuphathwa kwezibeletho, isb. ngenxa yezijoka, sifunda ukuthi yiziphi izinkomba nezinkomba zakhe.
Ukwakhiwa nomphumela wokwelapha we-injection Polyoxidonium
Isithako esisebenzayo se-Polyoxidonium yi-azoximer bromide, izinto eziwusizo: i-mannitol, i-povidone, i-beta-carotene. I-lyophilizate ikhishwa ngama-ampoules noma amabhodlela e-ingilazi ephelele ne-solvent efakwe kuma-ampoules, okungaba kokubili amanzi omjovo nesisombululo se-sodium chloride isotonic.
Lesi sidakamizwa sibonakala nge-bioavailability enhle kakhulu, singena ngokushesha egazini futhi sisakazwa kuzo zonke izicubu nezitho. Ngenxa yesenzo sezinto eziyinhloko zomuthi, ukumelana komzimba ezinkingeni ze-bacterial, viral and fungal kwanda. Lokhu kufezwa ngokugqugquzela ukubunjwa kwe-antibody yemvelo kumagciwane, kusebenze izinqubo zokukhiqiza kwamaseli avikelayo.
Ngokuhambisana nalokhu, i-detergent iye yaxosha futhi i-antioxidant izakhiwo ngenxa yesakhiwo se-Polyoxidonium. Ngenxa yalokhu, kwandisa ukumelana kwamangqamuzana amangqamuzana nemiphumela enobuthi yezidakamizwa namakhemikhali, kunciphisa ubuthi babo.
Izifo zokuzivikela i-Polyoxidonium zinikeza ithuba lokwandisa ukusebenza kahle nokunciphisa isikhathi sokwelashwa, ukunciphisa umthamo we-antibiotics, i-glucocorticosteroids, futhi nokwandisa isikhathi sokuxolelwa. Njengoba izifundo zibonisa, lesi sidakamizwa sibekezeleleke kahle, asinayo i-allergenic, i-carcinogenic, izakhiwo zomutageni.
Izinkomba zokusetshenziswa kwemijovo Polyoxidonium
Izijovo ze-Polyoxidonium zingenziwa uma amathuba okushisa, umkhuhlane kanye nezinye izifo zokuphefumula ezinzima ziphakeme ngenhloso yokuvimbela. Futhi ngezinhloso zokuvimbela, kuphakanyiswa ukusebenzisa umkhiqizo ngemuva kokusebenza nokulimala okwenziwe. Ngezinhloso zokwelapha, lesi sidakamizwa singasetshenziswa njengengxenye yokwelashwa okuyinkimbinkimbi nge:
- isifo sofuba;
- ukutheleleka kwe-herpesvirus;
- ukutheleleka kwe-bacterium urogenital;
- izifo ezithathelanayo nezifo ezingapheli (i- pollinosis , i-atopic dermatitis, i-asthma ye-bronchial, njll), ilukhuni nezinqubo ezithathelwanayo;
- I-arthritis ye-rheumatoid, okwesikhathi eside iphathwa nge- immunosuppressants ;
- izifo ezingokwemvelo ngesikhathi noma emkhakheni we-chemotherapy kanye nokwelashwa kwemisebe.
Indlela yokutshala izijovo ze-Polyoxidonium?
Ukuze uthole izijovo ze-intramuscular, i-ampoule ne-6 mg yesidakamizwa kufanele ihlanjululwe nge-1.5 - 2 ml ye-saline yemvelo noma amanzi alungisiwe. Ngomjovo omunwe we-ampoule lyophilizate, 6 mg ihlanjululwe nge-2 ml yesisombululo sezinto eziphilayo, i-hemodeza-H, i-rheopolyglucin noma isisombululo se-dextrose (5%), bese isisombululo sidluliselwa ku-dropper 200-400 ml. Kuyafaneleka ukucabangela lokho
Ukuqhathaniswa kwamagciwane Polyoxidonium:
- ukungaboni ngaso sonke isikhathi izingxenye zomuthi;
- ukukhulelwa;
- ukuncelisa.
Ngokuqapha, lesi sidakamizwa sisetshenziselwa ukuhluleka kwezinso, ukubekezelelana kwe-lactose, i-glucose-galactose malabsorption syndrome, ukuntuleka kwe-lactase.