I-hormone ye-antidiuretic noma i-hormone vasopressin i-peptide. Iqukethe izinsalela eziyisishiyagalolunye zama-amino acid. Ukuphila kwengxenye yayo imizuzu engu-2-4. Le hormone ikhiqizwa ezingxenyeni ezinkulu ze-hypothalamus, futhi kusukela lapho ithunyelwa ku-neurohypophysis. Ukuhamba kuyenziwa kuma-axon ngenxa yamaprotheni-vectors athile.
Imisebenzi ye-hormone vasopressin
Umsebenzi oyinhloko we-hormone ukulawulwa kwamanzi emzimbeni. Ngakho-ke, kuthiwa yi-antidiuretic. Uma inani le-ADH landa emzimbeni, umthamo we-urine okhishwe ngokukhululeka wehla.
Kodwa empeleni kuvela ukuthi i-vasopressin iyi-hormone enezinhlobo eziningi futhi imisebenzi emzimbeni yenza inani elimangalisayo. Phakathi kokubaluleke kakhulu kuzo:
- ukwandisa ivolumu yegazi ejikeleza ngemikhumbi;
- yanda ithoni ye-muscle ebushelelezi;
- umsebenzi owandayo wamaseli egazi wamaplatelet;
- ukulungiswa kwezinqubo zememori;
- ukunciphisa inani le-sodium egazini;
- oxidization of fatty acids.
Izindlela ze-vasopressin
Uma inani le-vasopressin lihambisana nokujwayelekile kwimiphumela yokuhlola, azikho izizathu zokukhathazeka. Izindinganiso ezijwayelekile zokubhekisela zibukeka kanje:
- nge-osmolality ye-plasma 270-280 mosm / kg -
- 280-285 mosm / kg -
- 285-290 mosm / kg - 1-5 pg / mol;
- 290-295 ama-mosm / kg - 2-7 pg / mol;
- 295-300 mosm / kg - 4-12 pg / mol.
Ngokomgomo wesenzo, ama-hormone vasopressin ne- oxytocin angacatshangwa kakhulu. Umehluko omkhulu wukuthi lo mlando uqukethe ama-residu amabili amino acid ngaphansi. Kodwa lokhu akuvimbeli i-hormone ukuthi ingabonakali umsebenzi omningi ngokuphathelene nokuvuselela ubisi, ngokwesibonelo.
Ukusebenza kwe-hormone vasopressin
Uma umuthi emzimbeni akwanele, isifo sikashukela esiphundu singakhula. Lesi sifo sibhekene nokucindezelwa komsebenzi wokuvuselelwa kwamanzi ngama-tubulus e-renal. Ukunciphisa izinga le-ADH kunconywa ukusetshenziswa kwe-ethanol ne-glucocorticoids.
Ukungasebenzi kahle kwe-hormone antidiuretic vasopressin
I-ADH ingenziwa ngokukhiqizwa ngamandla nge:
- ukucindezeleka ngokomzwelo nangokomzimba;
- ukwehluleka kwenqunu;
- ukungakwazi ukusebenza kahle ;
- ukwehla kwenani legazi elijikelezayo eduze kombhede wamasongo;
- i-porphyria ephakathi kakhulu;
- izicubu zobuchopho;
- i-pneumonia;
- i-meningitis ene-tuberculous.
Inkinga iyancipha ebunzini be-plasma yegazi kanye nokukhululwa komchamo wokuhlushwa okukhulu kakhulu.