I-Diuretics - izidakamizwa ezithinta ngqo izinso futhi zithinte ekususweni okusheshayo komchamo emzimbeni. Ngokuyinhloko, asetshenziselwa ukujwayelekile ukulinganisela kwe-asidi-base yomzimba, ukwelashwa kwezifo zenhliziyo, izifo zesimiso somchamo, ukufaka ushevu ngezinto ezinobuthi, njll. Ezimweni ezehlukene, izinhlobo ezithile ze-diuretics ziboniswa, indlela yokusebenza esekelwe ngezinqubo ezihlukahlukene. Ake sicabangele ukuthi yiziphi izimo eziphakanyiswayo ukusetshenziswa kwe-thiazide diuretics, nokuthi nokuthi zisebenza kanjani nokuthi yimiphi imithi ethulwe.
Indlela yokwenziwa kwe-thiazide diuretics
Lezi zidakamizwa ziyimithi yokusebenza okuphakathi komphumela, umphumela wayo ubhekwa cishe amahora angu-2-4 emva kokuphatha futhi uhlala cishe amahora angu-12. I-Thiazide diuretics ithinta ama-tubulus we-renal distal, ebonakala ngemiphumela elandelayo elandelayo:
- ukususwa kokuvuselelwa kabusha kwe-sodium ne-chlorine;
- ukwanda kwe-excretion ye-potassium ne-i-magnesium ion;
- ukwehla ekudonseni kwe-i-calcium ions kumchamo;
- ukwehla ekukhululweni kwe-uric acid, njll.
Ngokuvamile, i-thiazide diuretics inqunyelwe ukuthi:
- i-edema ehambisana nokuhluleka kwenhliziyo, isibindi se-fover and kidney;
- ne-hypertension engapheliyo yokunciphisa ukucindezelwa;
- isifo sikashukela insipidus ;
- i-glaucoma;
- i-idiopathic calciuria.
Ngezinye izikhathi lezi zidakamizwa zihlangene ne-loop diuretics, ezisiza ukunciphisa imiphumela yecala ehlobene nomthamo uphawu olulodwa lwalezi zinhlobo zemithi.
Uhlu lwe-Thiazide Diuretics
Uhlu lwezidakamizwa zesichungechunge se-thiazide luboniswa ngamalungiselelo ngezithako eziningana ezisebenzayo, okuyinhloko zazo:
- i-hydrochlorothiazide;
- indapamide ;
- i-clopamid;
- I-Chlorthalidone.