U-Amitriptyline uyisidakamizwa esicindezelayo esivela eqenjini lama-tricyclic compounds. It has a calming, analgesic, antihistamine, hypnotic, antiulcer effect. Ngokuvamise kakhulu lo muthi unqunywe ukucindezeleka kwezinto ezihlukahlukene ze-genesis, neuroses, psychoses kanye nezinye izimo ze-pathological.
Amaphilisi e-Amitriptyline anamandla ngokwanele ukukhiqiza imiphumela ehlelekile emzimbeni. Ngaphandle komthelela omuhle wokwelapha walesi sidakamizwa, okutholakala masinyane ngokwanele, iziguli eziningi ziphawula ukubukeka kwemiphumela emibi uma zisetshenziswa. Ezimweni eziningi, imiphumela emibi ivele ngemva kwezinsuku ezingu-1 kuya kwezingu-2 emva kokuqala kokwelashwa kwezidakamizwa. Cabanga ukuthi yimiphi imiphumela emibi ye-Amitriptyline, kungani ekhona, futhi obani abakwelashwa nalo muthi akuvunyelwe.
Imiphumela emibi ye-Amitriptyline
Ngokuvamile, ukubukeka kwemiphumela emibi ka-Amitriptyline kuhlotshaniswa nokudlula ngaphezulu (isilinganiso esiphezulu somuthi umuntu ngamunye). Futhi, zingahlobene nokuthi uma usebenzisa izidakamizwa umuntu uphenduka ngokucacile isikhundla sokulala esihlalweni nasekumi (konke ukunyakaza kufanele kube bushelelezi). Isenzo esibi sibonakaliswa nokuxhumana kuka-Amitriptyline neminye imithi. Phakathi kwabo kukhona:
- i-monoamine oxidase inhibitors;
- antipsychotics;
- ama-anticoagulants;
- i-glucocorticoids, njll.
Phakathi kwemiphumela emibi ka-Amitriptyline siyaphawula lokhu okulandelayo:
1. Kusukela eceleni kwesistimu yokugaya ukudla:
- ubuhlungu besisu;
- i-heartburn ;
- isicasuli;
- ukuhlanza;
- i-jaundice ngenxa yezinto eziqhakazile ezinkampanini zebhiliyari;
- izinkinga zesitoreji;
- izinguquko ekuboneni ukunambitha;
- umsebenzi wesibindi okhubazekile.
2. Kusukela ohlelweni lwesimo senhliziyo nesistimu ye-hematopoiesis:
- ukuhluleka kwenhliziyo;
- ukuncipha kwengcindezi yegazi;
- isiyezi;
- ukuphazanyiswa kwenqubo yokuqhuba yenhliziyo;
- kushintshwa kumaphesenti ama-erythrocyte, ama-leukocyte nama-platelet;
- izinguquko ku-electrocardiogram.
3. Kusukela ohlelweni lwesimiso:
- izindlu;
- ukuxhuma;
- ukuphelelwa amandla;
- ukulala noma ukulala;
- ukuvela kokunyakaza okungalawuleki kwezandla nezinyawo;
- ukudideka kokwazi;
- ukuthuthumela kwekhanda nemilenze;
- ikhanda;
- ukuxubha;
- i-wawning;
- ukuhlukunyezwa kwesisu;
- ukwehla nokwandisa ukuzwakalisa ukwesaba.
4. Kuyingxenye yesimiso se-endocrine:
- izinguquko kwisifiso sobulili;
- shintsha okuqukethwe kwe-glucose;
- ukwehla kokuqukethwe kwama-sodium ions;
- Ukwandiswa kwezilonda ezincelisayo.
5. Ezinye imiphumela emibi, kuhlanganise nalabo abahambisana nomthelela wokwelashwa komuthi:
- izinhlobo ezahlukene zokubonakaliswa kwegazi (i-angioedema, i-hives, itching, njll);
- ukunyuka kwe-intraocular;
- ukukhubazeka okubukwayo;
- umlomo owomile;
- umsindo ezindlebeni ;
- ukulahlekelwa kwezinwele;
- umkhuhlane;
- ukuvuthwa njalo, njll
Amitriptyline nokuphuza utshwala
Akunjalo neze iziphuzo zokuphuza utshwala zingadliwa uma uphatha lesi sidakamizwa. Ukusebenzisana kwe-amitriptyline nokuphuza utshwala kunomthelela ocindezelayo ohlelweni lwezinzwa zomphakathi, futhi ngokucindezeleka kwendawo yokuphefumula, kungabangela ukuphelelwa amandla nokufa.
Ukungafani kokuthatha i-Amitriptyline:
- ukukhulelwa kanye nokulahlwa;
- ukuhluleka kwenhliziyo esigabeni sokuqedela;
- i-infarction ye-myocardial (isigaba se-acute nesi-recovery);
- umfutho wegazi ophezulu;
- ukwephula ukuziphatha kwe-myocardial;
- isisindo esilula sezilonda zesilonda;
- isibindi nesifo sezinso ngesikhathi esiyinkimbinkimbi;
- ukwehlisa ithoni yezindonga zesikhumba;
- ukuvimbela amathumbu.