Ama-analogues e-Bisoprolol

I-bisoprolol yisidakamizwa esivame ukunikezwa iziguli ezinezifo zenhliziyo nesifo somfutho wegazi ophezulu.

Izimpawu zokusetshenziswa kwazo zilandelayo:

• ischemic isifo senhliziyo ( angina );
• ukucindezeleka komzimba;
• i-sinus tachycardia;
• ukuhluleka kwenhliziyo engapheli;
• ukuphazamiseka kwenhliziyo;
• i-arrhythmia ne-thyrotoxicosis ne-valve valve.

Njengeminye imithi, i-bisoprolol inezinhlobo zayo. Umphumela wabo oyinhloko ufana, bonke banciphisa ukucindezelwa kwegazi. Kodwa kukhona umehluko phakathi kwabo.

Yini engayenza esikhundleni se-bisoprolol?

Ama-analogos of the drug Bisoprolol afana nalokhu:

• I-Metoprolol;
• Carvedilol;
• Egilok;
• I-Betaxolol;
• Nebivolol;
• Ipropranolol.

Ngokuqhubekayo sizocabangela, ukuthi umehluko phakathi kwemithi-efana neBisoprolol.

Yini engcono - i-metoprolol noma i-bisoprolol?

I-Metoprolol iyinhlawulo eshibhile ye-bisoprolol. Ngakho-ke, izinkomba zokusetshenziswa kwazo zifana ngokufanayo. Ngabe kukhona umehluko phakathi kwalezi zidakamizwa? Kuvela ukuthi kukhona. Uma kuqhathaniswa nezakhiwo zabo zokwelapha, umuntu angafinyelela esiphethweni sokuthi i-bisoprolol inezinzuzo eziningana, esizoxoxa ngayo ngokuqhubekayo.

I-half-life ye-Bisoprolol ngamahora angu-10-12, futhi eMetoprolol kungamahora angu-3-4. Ngenxa yalokhu, i-bisoprolol ingathathwa kanye ngosuku, imvamisa yokudla kwe-metoprolol ngokuyinhloko kakhulu.

Ukubophezelwa kwe-metoprolol kuma-plasma amaprotheni kunama-88%, kuyilapho eBisoprolol lolu lwazi lufinyelela ku-30% kuphela. Futhi ngaphezu kwalesi sibonakaliso singaphansi, ukulungiselela kuphumelela kakhulu. Ngakho-ke, i-bisoprolol iyasebenza kakhulu.

I-bisoprolol i-beta-blocker yama-amphophilic, iyancibilika kokubili kwamanzi namafutha. Ngakho-ke, i-Bisoprolol ingena kancane emngceleni we-blood-brain futhi itholwe ngokulinganayo nezinso nesibindi. Ngesikhathi i-metoprolol idonswa isibindi kuphela, ngakho-ke, umthwalo okhona kulesi sitho uzoba mkhulu.

I-Carvedilol noma i-bisoprolol - engcono?

I-Carvedilol yinye isifanane se-Bisoprolol. Njenge-metoprolol, i-carvedilol i-metabolized kuphela esibindi. Ngakho-ke, ezigulini ezinezifo zesibindi, imvamisa yokudla izidakamizwa kanye nomthamo kufanele unciphise. Ngokungafani ne-Bisoprolol, i-Carvedilol kanye ne-Metoprolol ifinyelela umkhawulo wegazi, okwenza kube nemiphumela eminingi emibi evela ohlelweni lwezinzwa eziphakathi.

I-Bisoprolol noma i-Egiloc - okungcono?

Cishe u-5% wezidakamizwa u- Egilok badonswa emzimbeni ngomchamo. Okunye kukhishwa isibindi. Ngakho-ke, ukulungiswa kwesilinganiso kuyadingeka uma kunezinkinga zalesi sitho. Kwezinye izici, isenzo sezidakamizwa sifana, futhi umuntu angakwazi ukubeka endaweni ephephile.

Ngakho-ke, kungaphetha ngokuthi izenzo zezidakamizwa ezihlolwe zifana. Zonke zazo zingaphansi kwengcindezi yegazi kanye nenhliziyo. Kodwa izifundo zenziwa lapho iziguli zabhalwa ezingeni le-blood pressure emini. Ngakho-ke, ngenxa yalokho, kwatholakala ukuthi isidakamizwa seBisoprolol sigcine umphumela wokuhlaziywa kwemvelo emahoreni asekuseni ngosuku olulandelayo. Ezinye izifaniso azikwazanga ukuziqhayisa ngalokhu. Bamisa ngokuphelele noma bancishisa ukucindezeleka kwegazi okwezinyanga ezingu-3-4 ngaphambi kokuba umuthi olandelayo wezidakamizwa uthathwe.

Futhi, ucwaningo luye lwabonisa ukuthi i-Bisoprolol ilawula ngokuphumelelayo ukucindezelwa kwegazi nokulinganisa kwenhliziyo kokubili isimo esimweni sokuthula futhi ngaphansi kokusebenza ngokomzimba. Imiphumela yocwaningo iboniswa, ukuthi kulokhu i-Bisoprolol iyasebenza kakhulu, kuneMetoprolol.