I-glucocorticosteroid ingumuthi wemvelaphi yemvelo noma yokwenziwa. Libhekisela ku-subclass yama-hormone ku-cortex e-adrenal. Amalungiselelo avela eqenjini le-glucocorticosteroids anomthelela wokugonywa komzimba futhi akhulise ukwakheka kwe-glucose esibindi, ngakho-ke avame ukusetshenziselwa ukwelashwa kwezifo ezihlukahlukene.
I-glucocorticosteroids ithinta kanjani umzimba?
Okubaluleke kakhulu kwezinto eziphilayo ze-glucocorticosteroids ukukhulisa kakhulu ukumelana komzimba ukucindezeleka. Le mithi isetshenziselwa ukuvimbela ukuhlukunyezwa kwesimiso somzimba sokuzivikela, esiqondiswa kumzimba wakho. Lesi simo senzeke lapho ukuguqulwa komzimba, izicubu ezimbi nezifo ezizimele. Ngaphezu kwalokho, i-glucocorticosteroids ithinta i-mineral, amanzi, i-carbohydrate kanye neprotheyini yamathambo. Zibuye zisetshenziswe njengama-anti-inflammatory, antitoxic kanye nama-agents ahlaselayo. Kulashwa kungasetshenziswa izinhlobo ezinjalo zezidakamizwa:
- i-intranasal;
- i-parenteral;
- i-glucocorticosteroids engenele.
Le mithi inekhono lokuphakamisa umfutho wegazi. Iqaphela ngenxa yokwanda okukhulu ekukhululweni kwe-adrenaline, kanye nokunciphisa ukukhanya kweminye yegazi. Lokhu kuvumela ukusebenzisa i-glucocorticosteroids ukubhekana nama-shock states ezimweni ezibucayi ikakhulukazi.
Amagama ezidakamizwa ezivela eqenjini le-glucocorticosteroids
Kukhona amalungiselelo ambalwa kusuka eqenjini le-glucocorticosteroids, futhi amagama abanye ajwayele inani elikhulu labantu, ngoba asetshenziselwa ukuphatha izifo ezivamile. Amathuluzi athandwa kakhulu kulolu hlobo:
- I-Belogen - ukhilimu noma amafutha okusetshenziswa kwangaphandle. Isetshenziselwa i- eczema , ihlukanise neurodermatitis, i-atopic nezinye izidakamizwa.
- I-Sherisolone - amaphilisi ahlobene ne-glucocorticosteroids yesistimu. Isetshenziselwa ukwelapha i- scleroderma , i-nodular periarteritis, isifo se-rheumatoid arthritis.
- I-Cortonisol i-aerosol esetshenziselwa ukubola, isifo sikaCrohn, i-proctitis nesifo sofuba esiswini.
- I-Solu Medrol iyi-lyophilizate yokulungiswa kwesisombululo noma ukumiswa okwesikhashana kwegazi. It isetshenziselwa ukushisa nokusebenza ukushaqeka, ukusabela okusheshayo kwe-allergenic.
Isidakamizwa ngasinye esivela kuhlu lwe-glucocorticosteroids sinokuphikisana. Cishe noma iyiphi yazo akufanele isetshenziselwe isifo sikashukela, isifo se-Cushing, i-thromboembolism nokuhluleka okukhulu kwe-renal. Akudingekile ukuthi uphathe ukwelashwa nge-glucocorticosteroids ngesikhathi sokusebenza kwesifo sofuba nesifo sofuba.