I-Heptral iyisidakamizwa esinomphumela wesifo sofuba , esitholakala ngezindlela ezimbili: amaphilisi omlomo kanye nama-ampoules wokuphatha okungaphakathi noma kwe-intramuscular. I-Heptral yemithi ngama-ampoules yi-lyophilizate (i-powder) yokulungiselela isisombululo lapho i-solvent ekhethekile ihlinzekwa khona.
Isithako esisebenzayo salesi sidakamizwa i-ademethionine, into ephilayo equkethe zonke izicubu zomzimba. Idlala indima ebalulekile ezinkambisweni eziningi zezinto eziphilayo futhi ithuthukise ukwanda kwamandla amangqamuzana e-isibindi. Ukwakhiwa kwe-solvent kuhlanganisa izinto ezifana nalezi:
- L-lysine (i-amino acid);
- i-hydrodium i-sodium;
- amanzi alungisiwe.
Umphumela wamaphilisi we-injection nge-Heptral
Isenzo salesi sidakamizwa siqondiswa, okokuqala, ekubuyiseleni izinqubo zamangqamuzana kumaseli ase-hepatic nokuvuselelwa kwezicubu. Kodwa, ngaphezu kwalokho, i-heptral inegalelo elihle emisebenzini yobuchopho.
Ukwelashwa nge-Heptral njengesixazululo somjovo kwenza kube okulandelayo:
- ukukhiqizwa kwe-bile acid;
- ukuthuthukiswa kwe-motility yepheshana lezinsi;
- ukuphindwa kabusha kokuntuleka kwe-admetionin emzimbeni nokusebenza komkhiqizo wayo;
- ukuvikeleka kwamangqamuzana e-isibindi kusuka ebubilini;
- isithiyo sokusakazeka kwezicubu ezixhumene esibindi;
- ukuthuthukiswa kokuqhutshwa kwemizwa yezinzwa;
- ukuvuselelwa kwesistimu ye-nervous central, njll.
Izinkomba zokuqokwa kwe-heptral ku-ampoules
Amajojo we-heptral anconywa ngalezi zifo:
- i-hepatitis engapheli;
- i-fatty hepatosis ;
- cholecystitis engapheliyo;
- i-cholestasis ye-intrahepatic;
- i-cirrhosis yesibindi;
- i-cholangitis ;
- ukulimala kwesibindi semvelo enobuthi (viral, utshwala, izidakamizwa, njll);
- ukulimala komqondo ophilayo;
- i-abstinence syndrome (i-narcotic, utshwala, njll);
- ukucindezeleka.
Ukungahambisani nokusetshenziswa kwe-heptral
Ngokweziqondiso, i-Heptral ku-ampoules ayinqunyelwe kula macala alandelayo:
- ukukhulelwa (I-II trimesters);
- isikhathi sokuncelisa;
- ukungaboni ngaso sonke isikhathi izingxenye zomuthi;
- ukuntuleka kwe-cystathione-beta synthase;
- ukuphazamiseka kwemithi ye-cyanocobalamin.
Ngokucophelela, lesi sidakamizwa sinqunywe ukuhluleka kwenqunu, nokuphazamiseka kwe-bipolar, kanye neziguli ezigugile.