I-Allopurinol kanye nezifanekiselo zayo imithi enqunywe nge-uric acid eyengeziwe emzimbeni - hyperuricemia. Isifo ngokuvamile siholela ku-gout. Kunconywa imithi yeziguli ezingakwazi ukulawulwa kuphela ngokudla.
Amaphilisi e-Allopurinol nawo anikezelwe abantu abanesifo samatshe nesigcawu. Isetshenziselwa abantu abadala nabantwana abaneminyaka engaphezu kwengu-15 ubudala abanezibonakaliso zalezi zifo ngokumelene nesizinda se- leukemia , kanye nabantu abanenkinga yokuzalwa enzymatic.
Ungayifaka kanjani i-Allopurinol nge-gout?
Izilinganiso zesakhiwo se-Allopurinol:
- Allpol;
- Alopron;
- I-Sanphipurol.
Ingxenye eyinhloko i-oxypurinol, ephazamisa ukuguqulwa kwe-hypoxanthine ku-xanthine, bese ku-uric acid. Ngosizo lwezidakamizwa, izinga le-last in the urine kanye ne-system circulatory linciphisa. Lokhu kuvimbela ukuqoqwa kwamakristalu e-urate emzimbeni futhi kukhuthaza ukuhlelwa kabusha kwawo. Inani le-asidi liqala ukwehla kuphela ngosuku lwesine lokuthatha imithi. Umphumela ophezulu utholakala ngemva kwamasonto amabili.
I-Purinol nayo i-analog yesakhiwo se-Allopurinol. Phakathi nokuphathwa kwezidakamizwa, i-synthesis of uric acid iyancipha, okuholela ekunciphiseni kwayo emithonjeni yamanzi emzimbeni. Ngaphezu kwalokho, idiphozithi ekhona ye-urate ivele yachithwa futhi ukubunjwa kabusha kwazo ezinso nezinhlanzi kuvinjelwe. Uma uthola i-Purinol, ukucinwa kwe-xanthine ne-hypoxanthine emcinini kwanda. Imiphumela yomuthi incike kumthamo obekiwe.
Ukungahambisani nokusetshenziswa kwe-Allopurinol nezifanekiselo zayo
I-Allopurinol nezifanekiselo zayo, ezinqunyelwe i- gout , zinezinombolo eziningi zokuphikisana, ezibonakaliswa ezimweni ezilodwa. Ngakho-ke, isibonelo, kwakukhona iziguli ezakha i-bradycardia nomfutho wegazi ophezulu. Kwezinye izimo, kwakukhona:
- ukuhlanzeka nokuhlanza;
- isifo sohudo;
- i-hepatitis;
- i-stomatitis;
- i-steatorrhea.
Cishe ngaso sonke isikhathi lokhu kwakuhambisana no:
- ubuthakathaka;
- ukhathala okwandayo;
- ikhanda;
- i-ataxia;
- isiyezi.
Okungavamile - ukwephulwa kombono kanye nokunambitheka kokunambitheka, ukuphazamiseka kwengqondo, ukugula, ukucindezeleka kanye ne-coma.
Ngenkathi yokwelashwa, iziguli ezaba nesifo sokuzibulala ngesimo sokukhwabanisa isikhumba, i-hyperemia, i-pruritus, i-fever ne-fever nazo zaphawulwa. Kwezinye izimo, abantu bahlakulela izinwele ze-furunculosis nezinwele.
Uma kunesidingo, ochwepheshe batusa ukuthatha i-Allopurinol kuphela, futhi uma udinga ukuyibeka endaweni ethile, kufanele usebenzise kuphela ama-analogues ekhwalithi. Uma kungenjalo, kungaba nomthelela omubi emsebenzini wesibindi kanye nomzimba wonke.