I-Pradaxa iyisidakamizwa esiseqembu lama-anticoagulant kanye ne-antithrombotic izidakamizwa. Basebenzisa ngama-orthopedics kanye ne-traumatology esikhathini esilandelayo ikakhulukazi ekuvimbeleni i-thromboembolism ye-venous.
Amandla okusebenzisa i-Pradax
Into esemqoka yokusebenza yalesi sidakamizwa i-dabigatran etexilate. Ngenxa yalokhu, umsebenzi we-thrombin uphelelwa ngemuva kokusebenzisa ukulungiswa kwe-Pradax. I-dabigatran etexilate isheshe igxilwe futhi iguqulwe ibe i-dabigatran (i-inhibitor eqondile eguquguqukayo eguquguqukayo) ngesikhathi se-hydrolysis. Ukusebenza komuthi kuncishiswe ngama-20% uma isisindo somuntu singaphezu kuka-120 kg, futhi sanda ngo-25% ngesisindo somzimba wesiguli esingaphansi kwama-48 kg.
Izinkomba zokusetshenziswa Pradax ziyi:
- ukuvimbela i-thromboembolism ye-venous;
- ukuvimbela i- thromboembolism ehlukahlukene yesistimu;
- ukuvimbela izifo zenhliziyo ezigulini ezine-fibrillation e-atrial.
Ukusetshenziswa kwe-Pradax kuboniswa cishe kuzo zonke iziguli ezinokuhlolwa okunjalo ngemva kokusebenza kwamathambo, kusukela kuwo wonke ama-coagulants anamuhla lalesi sidakamizwa kubhekwa ukuthi siyasebenza kakhulu. Futhi, le mithi inqunywe emva kokuphela kwamadolo okuphela komzimba. Ukwamukelwa ukutakula okusheshayo komzimba kufanele kuqale amahora angu-1-4 ngemuva kokuphela kokusebenza.
Ukungahambisani nokusetshenziswa kwe-Pradaxi
Ngisho noma unezinkomba zokusebenzisa imithi kaPradax, awukwazi ukuyisebenzisa ekwelapheni kwe-hypersensitivity kunoma yiziphi izingxenye zomuthi. Ungaqali ukuthatha le mithi ngesimo esibi sezinso zezinso, ukuphazamiseka okuzenzekelayo noma okubangelwa yi-homeostasis kanye nokuphuma kwegazi okuphawulekayo.
Ukungahambisani nokusetshenziswa kwePradax nakho:
- umsebenzi wesibindi okhubazekile;
- ukuhlukumeza komgogodla nobuchopho;
- i-neoplasms eyingozi;
- ukubola kwesisu;
- isilonda esiswini;
- izinkinga ze-intracerebral vascular.
Akunconywa ukusebenzisa lesi sidakamizwa kanyekanye nama-antiplatelet agents. Le nhlanganisela iyingozi empilweni, ngoba yandisa kakhulu ingozi yokugaya cishe cishe kathathu. Uma kukhona ubufakazi bokusetshenziswa kwe-Pradax nodokotela banquma ukubeka lo muthi, ngakho-ke kuyadingeka ukukhansela ukungena kwanoma yiziphi ezinye izinhlobo ze-anticoagulants. Akunconywa ukwenza ukwelashwa ngaleyo mithi yeziguli ezingaphansi kweminyaka engu-18 ubudala, ngoba akukho idatha yomtholampilo emiphumeleni yokusetshenziswa kwayo kule minyaka iyatholakala.